Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Protocols
Every protocol is sourced from a specific person, paper, or label. Filter by goal, experience level, or confidence tier to find protocols that match where you are. Pick one, set a start date, and the schedule runs on your calendar.
14 researchers, clinicians, and public figures
Wolverine, GLOW, Never Get Sick, and more
All Protocols
Ipamorelin + Tesamorelin + BPC-157 +2
Five peptides from the co-author of Jay Campbell's Peptide Cheat Sheet. Hunter Williams disclosed his personal protocol: Ipamorelin 300mcg, Tesamorelin 1mg, BPC-157 500mcg, TB-500 500mcg, and TA-1, all cycled 8 weeks on and 8 weeks off. The dosing lines up with the cheat sheet he co-wrote, which adds credibility. He also runs Tirzepatide 0.5mg three times per week but that sits outside the core stack. Budget $300-600/month.
BPC-157 + TB-500 + Ipamorelin +2
Five peptides, three sub-stacks, and a torn hamstring that started it all. Ben Greenfield published full dosing for BPC-157, TB-500, ipamorelin, tesamorelin, and GHK-Cu after using the combo to recover from a persistent upper leg injury. The healing duo (BPC-157 + TB-500) can be run alone; the GH pair (ipamorelin + tesamorelin) adds recovery optimization at bedtime. Budget $400-800/month and plan for 4-12 weeks on, equal time off.
GHK-Cu + BPC-157 + TB-500
Three peptides blended in a 5:1:1 ratio: GHK-Cu (50mg), BPC-157 (10mg), and TB-500 (10mg) in a single 70mg vial. Jay Campbell published the GLOW protocol for tissue repair, gut healing, and skin rejuvenation. Available as a pre-blended vial or mixed individually. Daily injection, with at least 15 days off between cycles. The source gives receptor desensitization as the reason for the break; no desensitization data exists for these three compounds. Beginner-friendly entry point.
Thymosin Alpha 1 + BPC-157 + Epithalon
Three peptides for immune modulation, gut healing, and telomere maintenance. TA-1 at clinical dose (1.6mg 2x/week), oral BPC-157 for gut health, and Epithalon in 10-day pulses. Note: Holtorf co-founded a company that sells oral BPC-157.
BPC-157 + TB-500
Gold-standard healing combination. BPC-157 for local tissue repair + TB-500 for systemic healing. 6-week protocol with TB-500 loading then maintenance.
BPC-157 + Ipamorelin + Tesamorelin
One syringe, three peptides, taken at bedtime. Dr. Koniver confirmed on Huberman Lab Ep 197 that he combines BPC-157 (500mcg), ipamorelin (100mcg), and tesamorelin (2mg) in a single subcutaneous injection. Schedule is 5 days on, 2 off. No food for 45 minutes before. The single-syringe detail settled a long-running debate about whether these peptides could be mixed safely.
Epithalon + BPC-157
A biochemist's anti-aging approach: Epithalon at ~3.3-5mg/day for 20-30 days (100mg total per cycle, 2-3x/year) plus BPC-157 in two modes: 10mg monthly high-dose pulse or 250mcg daily for 2 weeks on / 6 weeks off. Tremblay owns CanLab and has 30+ years in peptide manufacturing.
BPC-157
The only peer-reviewed human BPC-157 clinical trial, published in Alternative Therapies (2021). Dr. Edwin Lee injected 4mg BPC-157 directly into knee joints. Seven out of 12 patients reported pain relief lasting 6+ months from a single injection. The route is intra-articular, not subcutaneous. This is a physician-administered procedure, not a self-injection protocol.
BPC-157
Huberman used BPC-157 for an L5 disc compression from deadlifting and reported resolution in "approximately 2 injections" after massage, heat, and electrical stimulation had all failed. Dose is a discussed range (300-500mcg, 2-3 times per week), not his exact personal dose. Sourced from Huberman Lab Ep 170. Cycle 8 weeks on, 8-10 weeks off.
BPC-157
Conservative 6-week healing protocol using beginner-tier dosing. Inject near injury site for local repair or abdomen for systemic/gut effects.
GHRP-6 + CJC-1295 (No DAC) + Ipamorelin +3
Six peptides across 5 timed injections per day for 12 weeks. Three GH secretagogues (GHRP-6 morning, ipamorelin pre-workout, GHRP-2 evening) plus CJC-1295 twice daily, AOD-9604 fasted, and TB-500 twice weekly. Aggressive stacking from a supplement company founder.
SS-31 (Elamipretide) + Epithalon + Thymosin Alpha 1 +1
Four peptides, four aging mechanisms, 30 days. Ben Pakulski targets mitochondria with SS-31 (10mg daily), telomeres with Epithalon (5mg, 5x/week), immune function with TA-1 (1.5mg daily), and senescent cells with FOXO4-DRI (10mg EOD for 2 weeks). The FOXO4-DRI dose is 3.3x the standard aggressive tier. Budget $500-1,200 and consider starting with 1-2 peptides rather than all four simultaneously.
TB-500 + Thymalin + LL-37
Three peptides, three different cycle lengths, one goal: stop getting sick. Greenfield pairs TB-500 (3 months on, 3 off) with Thymalin (3-10 day bursts every 6-12 months) and LL-37 (4-6 week antimicrobial cycles). Each targets a different layer of immune defense. Warning on LL-37: Herxheimer reactions are common in the first two weeks if you have SIBO or gut dysbiosis.
Epithalon + Thymosin Alpha 1
Epithalon at 5mg daily for 10 days (2x/year) as his "#1 longevity peptide," plus TA-1 at a lower-than-standard 250mcg maintenance dose (1-2x/week, daily when sick). Discussed on the Dr. Hyman Show podcast.
Epithalon + Thymosin Alpha 1
Bryan Johnson's thymus rejuvenation protocol from Project Blueprint. Epithalon (10mg/day) and Thymosin Alpha-1 (1.5mg/day) injected IM for 5 consecutive days, then nothing for 6 months. Follows the Khavinson protocol. Dosing sourced from tweets; the original post had ambiguous wording that the community later resolved. Budget $100-250 per pulse cycle.
TB-500
Standard loading + maintenance cycle: 4 weeks at full dose (2x/week), then 4 weeks maintenance at half dose (1x/week). Systemic — injection site does not matter.
CJC-1295 (No DAC) + Ipamorelin
Campbell's recommended starting point for newcomers. CJC-1295 (no DAC) plus ipamorelin at bedtime, 5 on / 2 off, 8 weeks on and 8 off. He calls it "extensively studied." The same combo shows up in both his muscle growth and fat loss stack lists, which tells you something about its versatility.
Semaglutide + Tirzepatide
Peter Attia prescribes GLP-1 agonists clinically and flagged the lean mass loss problem early: 39% of weight lost in the STEP 1 trial was lean tissue. His protocol follows standard FDA titration (0.25mg to 1mg+ weekly) but pairs it with resistance training and 1g protein per pound of bodyweight. This is a prescriber's perspective, not personal biohacking. DEXA scans and metabolic panels required.
CJC-1295 (DAC) + MK-677 (Ibutamoren)
Derek's approach to replicating pharma-grade GH IGF-1 levels without actual GH. CJC-1295 DAC at 2.5mg twice weekly (Monday and Thursday) plus MK-677 at 25mg daily oral, both at bedtime. Target: IGF-1 around 500 ng/mL. The CJC-1295 DAC dose exceeds standard ranges. Regular IGF-1 bloodwork and fasting glucose monitoring required. Advanced users only.
Semaglutide
Semaglutide at 0.025-0.05mg weekly, roughly 1/10th the standard starting dose. Dr. Tyna Moore's philosophy: "Dose up to appetite control, not suppression." Exact microgram dose is not publicly verified; the approach and philosophy come from multiple interviews including Ben Greenfield Life. She treats GLP-1 as scaffolding for building metabolic habits, not a permanent prescription.
Semaglutide
FDA-standard weekly titration from 0.25mg to 2.4mg over 16+ weeks. Hold current dose for an extra 4 weeks if GI side effects are severe.
Tirzepatide
Three weeks, then done. Johnson tried tirzepatide at 0.5mg weekly (1/5th the standard starting dose) and halted when his data turned negative: resting heart rate up 3bpm, HRV down 7 points, sleep quality down 10%. He already had optimal metabolic markers, so the risk outweighed any benefit. This is some of the best-documented peptide discontinuation data available, with exact biomarker numbers attached.
Tirzepatide
FDA-standard weekly titration from 2.5mg to 15mg. Many maintain at 7.5-10mg without reaching max dose.
Sermorelin
Two years on sermorelin for deep sleep, then he stopped. Huberman tracked everything with Eight Sleep and WHOOP; the data showed REM sleep depletion and elevated PSA (prostate-specific antigen). He disclosed this on Ep 170 as cautionary data. Dose is a discussed range, not his exact personal dose. This protocol is discontinued, but the discontinuation data is what makes it worth studying.
Cerebrolysin
Bryan Johnson called cerebrolysin "the best subjective neuro-enhancer" he's tried, then added that it produced no measurable biomarker improvement. Phase 1: 5mL IM every other day (10 injections over 20 days). Phase 2: 5mL IM daily for 3 months. Porcine-derived, so not suitable for pork allergies. The gap between subjective experience and objective data is the interesting part here.
Retatrutide
Phase 3 trial protocol: weekly titration from 1mg to 12mg. Triple GLP-1/GIP/Glucagon agonist with up to 24% weight loss in clinical trials.
How Protocols Work
Find a protocol that matches your goal. Check the evidence tier and read the phase breakdown.
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Log each dose, track your progress, and export your schedule. The protocol runs on your calendar.