Not medical advice. Talk to your provider before using any peptide.
Full disclaimerHuberman BPC-157 Protocol — Injury Recovery Dosing from Ep 170
Huberman used BPC-157 for an L5 disc compression from deadlifting and reported resolution in "approximately 2 injections" after massage, heat, and electrical stimulation had all failed. Dose is a discussed range (300-500mcg, 2-3 times per week), not his exact personal dose. Sourced from Huberman Lab Ep 170. Cycle 8 weeks on, 8-10 weeks off.
Peptide Schedule Research TeamReviewed Apr 2026
For injury recovery using subcutaneous BPC-157, based on dosing ranges discussed on Huberman Lab Ep 170.
What This Protocol Does
BPC-157 injected subcutaneously near the injury site at 300-500mcg per injection, 2-3 times per week for 8 weeks. Huberman reported using it for an L5 disc compression that didn't respond to massage, heat, or electrical stimulation. He described resolution in roughly 2 injections. The protocol cycles 8 weeks on, 8-10 weeks off.
Who Should Use This
Intermediate users dealing with musculoskeletal injuries, tendon issues, or joint pain. Budget $60-150 per month for BPC-157 alone. Good entry point for first-time peptide users since it involves only one peptide. Avoid with active cancer or cancer history (BPC-157 promotes angiogenesis via VEGF upregulation). Consult a physician before starting.
What the Research Says
BPC-157 has over 100 preclinical studies demonstrating tissue repair, tendon healing, and gastrointestinal protection (Sikiric et al., PMID 9073154). One human clinical trial exists (Lee and Bhatt, 2021, PMID 34324435) using intra-articular injection for knee pain. No completed human trials exist for subcutaneous dosing at this range. Community reports consistently describe accelerated recovery from soft tissue injuries within 1-4 weeks. The FDA moved BPC-157 to Category 2 in October 2023, restricting it from compounding pharmacies.
Important Notices
- Dose is a discussed range, not Huberman's exact personal dose
- BPC-157 moved to FDA Category 2 (restricted from compounding) Oct 2023
- Risk of tumor growth via VEGF/angiogenesis upregulation
- No completed human clinical trials
Protocol Overview
8 weeks totalSupplies Needed
- Insulin syringes (29-31g)
- Bacteriostatic water
- Alcohol swabs
Contraindications
- Active cancer or history of cancer
- Pregnancy or breastfeeding
What to Expect
Dosing Details
| Peptide | Dose | Frequency | Route | Weeks |
|---|---|---|---|---|
| 400mcg | Custom Schedule | subcutaneous (near injury site) | Weeks 1-8 |
BPC-157: 300-500mcg per injection, 2-3x/week. Discussed range — not exact personal dose.
Metrics Tracked
Schedule This Protocol
Set your start date and track every dose in your calendar.
Peptide Profiles & Calculators
Related Healing & Recovery Protocols
BPC-157 Conservative Healing Protocol
BPC-157
Conservative 6-week healing protocol using beginner-tier dosing. Inject near injury site for local repair or abdomen for systemic/gut effects.
TB-500 Loading + Maintenance Protocol
TB-500
Standard loading + maintenance cycle: 4 weeks at full dose (2x/week), then 4 weeks maintenance at half dose (1x/week). Systemic — injection site does not matter.
Healing Stack: BPC-157 + TB-500
BPC-157 + TB-500
Gold-standard healing combination. BPC-157 for local tissue repair + TB-500 for systemic healing. 6-week protocol with TB-500 loading then maintenance.
Wolverine Stack
BPC-157 + TB-500 + Ipamorelin +2
Five peptides, three sub-stacks, and a torn hamstring that started it all. Ben Greenfield published full dosing for BPC-157, TB-500, ipamorelin, tesamorelin, and GHK-Cu after using the combo to recover from a persistent upper leg injury. The healing duo (BPC-157 + TB-500) can be run alone; the GH pair (ipamorelin + tesamorelin) adds recovery optimization at bedtime. Budget $400-800/month and plan for 4-12 weeks on, equal time off.
Never Get Sick Stack
TB-500 + Thymalin + LL-37
Three peptides, three different cycle lengths, one goal: stop getting sick. Greenfield pairs TB-500 (3 months on, 3 off) with Thymalin (3-10 day bursts every 6-12 months) and LL-37 (4-6 week antimicrobial cycles). Each targets a different layer of immune defense. Warning on LL-37: Herxheimer reactions are common in the first two weeks if you have SIBO or gut dysbiosis.
Dr. Koniver's GH Secretagogue Bedtime Stack
BPC-157 + Ipamorelin + Tesamorelin
One syringe, three peptides, taken at bedtime. Dr. Koniver confirmed on Huberman Lab Ep 197 that he combines BPC-157 (500mcg), ipamorelin (100mcg), and tesamorelin (2mg) in a single subcutaneous injection. Schedule is 5 days on, 2 off. No food for 45 minutes before. The single-syringe detail settled a long-running debate about whether these peptides could be mixed safely.