Peptide ScheduleBest Peptides for Anti-Aging
The most effective peptides for longevity, skin rejuvenation, and cellular age reversal — from telomere protection to collagen stimulation.
Epithalon
The only peptide that directly activates telomerase to lengthen telomeres — the protective caps on chromosomes that shorten with age. Short intensive cycles (10-20 days) produce effects that last months.
- Direct telomerase activation
- Short cycles with lasting effects
- Normalizes melatonin production
- Over 20 years of research
- Preclinical data primarily from Russian literature
- Effects are subtle and long-term
- No FDA approval or human trials
GHK-Cu
The most versatile anti-aging peptide. GHK-Cu stimulates collagen/elastin production, activates 4,000+ repair genes, promotes wound healing, and supports hair regrowth. Available both as injectable and topical.
- Injectable and topical formulations
- Visible skin improvements
- Hair regrowth support
- Extensive gene expression research
- Short half-life (~1 hour)
- Avoid with copper sensitivity
- Topical effects are slower than injectable
NAD+
NAD+ is a critical coenzyme for cellular energy production and DNA repair. Levels decline 50% by age 60. Supplementing NAD+ restores mitochondrial function and activates sirtuins — longevity-associated proteins.
- Restores cellular energy production
- Activates sirtuin longevity pathways
- Improves cognitive function
- Supports DNA repair
- IV/SC injections can sting
- Expensive for regular use
- Optimal dosing still being researched
How We Ranked These
Ranked by mechanism specificity for aging pathways (telomeres, gene expression, mitochondria), research depth, and practical accessibility. Peptides targeting fundamental aging processes score highest.
Beginner Recommendation
Start with Epithalon (short cycle) + GHK-Cu (daily) + NAD+. This covers telomeres, gene expression, and cellular energy — the three pillars of anti-aging.
View Anti-Aging Stack→