Peptide ScheduleAnti-Aging Peptides
Longevity peptides targeting telomeres, mitochondria, and cellular regeneration.
Anti-aging peptides target the biological processes behind aging: telomere shortening, mitochondrial decline, and oxidative damage. They won't reverse your age, but they may slow down cellular wear and support healthier aging.
Epithalon (Epitalon) is the standout here. It activates telomerase — the enzyme that maintains your telomere length. Shorter telomeres are linked to aging, so keeping them intact is a big deal in longevity research. GHK-Cu is a copper peptide that boosts collagen, reduces wrinkles, and supports wound healing.
NAD+ and SS-31 (Elamipretide) take a different angle. NAD+ supports mitochondrial energy production — levels drop as you age. SS-31 targets the inner mitochondrial membrane directly. Both are still early in human research but show promise in preclinical studies.
Quick Comparison
| Peptide | Route | Frequency | Half-Life | Status | Grade |
|---|---|---|---|---|---|
| Argireline | Topical | 2x Daily | Unknown | Research | A |
| Epithalon | SubQ | Daily | ~30 minutes | Research | A |
| GHK-Cu | Topical | Daily | ~1 hour | Research | A |
| Glutathione | SubQ | 2x/week | ~10 min | Research | A |
| Matrixyl | Topical | Daily | Unknown | Research | A |
| Matrixyl 3000 | Topical | Daily | ~6 hours | Research | A |
| Syn-Ake | Topical | Daily | Unknown | Research | A |
| NAD+ | SubQ | 2x/week | ~2-4 hours | Research | B |
| SNAP-8 | Topical | Daily | Unknown | Research | B |
| SS-31 (Elamipretide) | SubQ | Daily | ~4 hours | FDA Approved | B |
| AHK-Cu | Topical | Daily | ~1-2 hours | Research | C |
| Endoluten | Oral | Daily | ~2-4 hours | Research | C |
| FOXO4-DRI | SubQ | 3x/week | ~2-4 hours | Research | C |
| Humanin | SubQ | EOD | ~30 min in mice | Research | C |
| IGF-1 LR3 | SubQ | Daily | ~20-30 hours | Research | C |
| PTD-DBM | Topical | Weekly | ~2-4 hours | Research | C |
All Anti-Aging Peptides(16)
Epithalon
Epithalon (Epitalon) is a tetrapeptide that activates telomerase, the enzyme responsible for lengthening telomeres — ...
GHK-Cu
GHK-Cu is a naturally occurring copper-binding tripeptide that declines with age.
Glutathione
Glutathione is the body's master antioxidant — a tripeptide produced in every cell.
IGF-1 LR3
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified version of IGF-1 with a much longer half-life and grea...
NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell, essential for energy production,...
SS-31 (Elamipretide)
SS-31 (Elamipretide) is a mitochondria-targeted peptide that binds to cardiolipin on the inner mitochondrial membrane.
FOXO4-DRI
FOXO4-DRI is a D-retro-inverso peptide engineered to selectively eliminate senescent cells — often called "zombie cel...
SNAP-8
SNAP-8 (Acetyl Octapeptide-3) is an eight-amino-acid peptide designed to reduce the appearance of expression lines an...
AHK-Cu
AHK-Cu (Copper Tripeptide-3) is a synthetic copper-binding peptide composed of alanine, histidine, and lysine chelate...
Humanin
Humanin belongs to a small but growing class of mitochondrial-derived peptides — bioactive molecules encoded directly...
Matrixyl
Matrixyl (Palmitoyl Pentapeptide-4, Pal-KTTKS) is a five-amino-acid peptide with the sequence lysine-threonine-threon...
Endoluten
Endoluten is a pineal gland peptide bioregulator developed as part of Vladimir Khavinson's decades-long research prog...
Argireline
Argireline (Acetyl Hexapeptide-8, formerly Acetyl Hexapeptide-3) is a synthetic six-amino-acid peptide with the seque...
Syn-Ake
Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate, Tripeptide-3) is a synthetic tripeptide engineered to mimic...
PTD-DBM
PTD-DBM (Protein Transduction Domain-fused Dishevelled Binding Motif) is a synthetic peptide developed at Yonsei Univ...
Matrixyl 3000
Matrixyl 3000 is a patented dual-peptide complex developed by Sederma that combines Palmitoyl Tripeptide-1 (Pal-GHK, ...