How many units of MOTS-c should I draw?

It depends on your vial size, BAC water, and dose. For a 5mg vial with 2mL BAC water, a beginner dose of 5000mcg is typically 200 units on a U-100 syringe. Use the calculator above for your exact numbers.

How much BAC water should I add to MOTS-c?

The standard amount is 2mL of bacteriostatic water for a 5mg vial. More water gives a more dilute solution — easier to measure small doses. Less water means fewer injections per vial. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

How long does a MOTS-c vial last?

At a beginner dose of 5000mcg 3x/week, a 5mg vial lasts about 1 doses. The calculator shows exact doses per vial for your selected tier.

What syringe should I use for MOTS-c?

Most people use a U-100 insulin syringe (1mL / 100 units). For very small doses, a U-50 or U-30 syringe gives better precision. The calculator adjusts units automatically for whichever syringe you pick.

MOTS-c Dosage Calculator

MetabolicInjectionPreclinical~12-15 hours half-life

MOTS-c is a mitochondria-derived peptide encoded in mitochondrial DNA — making it one of the few known mitochondrial-encoded signaling molecules.

Exercise mimetic — activates workout pathwaysImproves insulin sensitivityEnhances fatty acid oxidation (fat burning)Boosts exercise capacity and endurance

Vial Size

BAC Water (mL)

Dosing Level

5mg · 3x/week

Custom Dose (mcg) — optional

Syringe Type

200.0 units

100 units (1mL)

Concentration

2,500

mcg/mL

Draw Volume

2.000

Syringe Units

200.0

units

Doses / Vial

doses

Draw (200.0 units) exceeds U-100 capacity (100 units). Use a larger syringe or add more BAC water.

Summary: Add 2mL BAC water to your 5mg vial. Draw to 200.0 units on a U-100 syringe for a 5mg dose. This vial will last 1 doses.

Cycle Planner

Cycle Length (weeks)

Price Per Vial ($) — optional

Subcutaneous. Typical beginner frequency: 3x/week.

MOTS-c Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~12-15 hours

After 1 half-life (14h): 50% remainsAfter 2 half-lives (27h): 25% remainsAfter 3 half-lives (41h): 12.5% remains

At a 10mg dose: 50% = 5.0mg remaining after 14h. Recommended frequency: 3x/week.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

MOTS-c Dosing Protocol

Level	Dose / Injection	Frequency
Beginner	5mg	3x/week
Moderate	10mg	3x/week
Aggressive	10mg	5x/week

Note: Mitochondria-derived peptide. Enhances AMPK activation and fatty acid oxidation. Commonly cycled 4 weeks on, 2 weeks off. May improve insulin sensitivity.

About MOTS-c

MOTS-c is a mitochondria-derived peptide encoded in mitochondrial DNA — making it one of the few known mitochondrial-encoded signaling molecules. It acts as an 'exercise mimetic,' activating AMPK (the same pathway triggered by exercise) to improve metabolic function. Research shows it enhances insulin sensitivity, promotes fatty acid oxidation, and improves exercise capacity even without training.

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