Peptide ScheduleCognitive Peptides
Nootropic peptides for focus, memory, anxiety reduction, and neuroplasticity.
Cognitive peptides target focus, memory, anxiety, and neuroplasticity. Unlike stimulants, they don't give you a jolt — they work on neurotrophic factors like BDNF that support long-term brain health.
Semax and Selank are the two most popular options. Both were developed in Russia and have clinical approval there. Semax boosts BDNF (brain-derived neurotrophic factor), which supports learning and memory formation. Selank targets anxiety and mood through GABA modulation — think of it as the calming counterpart to Semax's focus enhancement.
Both are delivered as nasal sprays, which means no injections. They cross the blood-brain barrier quickly through the nasal mucosa. If you're new to peptides and needle-averse, this category is a good starting point.
Quick Comparison
| Peptide | Route | Frequency | Half-Life | Status | Grade |
|---|---|---|---|---|---|
| Cyclic Glycine-Proline (cGP) | Oral | Daily | ~4-6 hours | Preclinical | A |
| Selank | SubQ | Daily | ~2-3 min | Research | A |
| Semax | SubQ | Daily | ~2-3 min | Research | A |
| Cerebrolysin | IM | Daily | ~2-4 hours | Research | B |
| Cortexin | IM | Daily | ~1-3 hours | Research | B |
| FGL (FG Loop Peptide) | SubQ | 5x/week | ~4-6 hours | Phase 1 | B |
| MIF-1 (Pro-Leu-Gly-NH2) | SubQ | Daily | ~2 hours | Research | B |
| NA-Selank Amidate | Nasal | 2x Daily | ~2-3 min | Research | B |
| NA-Semax Amidate | Nasal | Daily | ~5-10 min | Research | B |
| Omberacetam (Noopept) | Oral | Daily | ~15-20 min | Research | B |
| Beta-Endorphin | SubQ | EOD | ~20-35 minutes | Research | C |
| Bromantane (Ladasten) | Oral | Daily | ~11 hours | Research | C |
| Cerluten | Oral | Daily | ~1-3 hours | Research | C |
| Cortagen | Oral | Daily | ~0.5 hours | Research | C |
| Dihexa | SubQ / Oral | Daily | ~12.7 days | Research | C |
| DNSP-11 | Nasal | Daily | ~24+ hours | Research | C |
| P21 | Nasal | Daily | ~3+ hours | Research | C |
| PE-22-28 | Nasal | Daily | ~23 hours | Research | C |
| Pinealon | SubQ / Oral | Daily | ~15-30 minutes | Research | C |
All Cognitive Peptides(19)
Selank
Selank is a synthetic peptide based on the naturally occurring immune molecule tuftsin, developed at the Institute of...
Semax
Semax is a synthetic peptide analog of ACTH (adrenocorticotropic hormone) developed in Russia for stroke treatment an...
Cerebrolysin
Cerebrolysin is a porcine brain-derived peptide preparation manufactured by EVER Neuro Pharma.
Dihexa
Dihexa (N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, also called PNB-0408) is a small peptidomimetic derived from angi...
NA-Semax Amidate
NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of the Russian nootropic peptide Semax, engineered wi...
Pinealon
Pinealon is a synthetic tripeptide bioregulator composed of L-glutamic acid, L-aspartic acid, and L-arginine (Glu-Asp...
PE-22-28
PE-22-28 is a synthetic heptapeptide (7 amino acids) derived from spadin, a naturally occurring fragment of the sorti...
P21
P21 (also designated P021) is a synthetic tetrapeptide derived from the biologically active region of human ciliary n...
DNSP-11
DNSP-11 (Dopamine Neuron Stimulating Peptide-11) is a synthetic 11-amino-acid peptide derived from the proprotein reg...
Bromantane (Ladasten)
Bromantane (N-(4-bromophenyl)adamantan-2-amine) is a synthetic actoprotector developed at the Russian Academy of Medi...
Omberacetam (Noopept)
Omberacetam (Noopept, GVS-111) is a synthetic dipeptide nootropic developed in Russia as a cognitive enhancer and neu...
Cortexin
Cortexin is a polypeptide bioregulator complex derived from the cerebral cortex of young cattle or pigs through acid ...
Cyclic Glycine-Proline (cGP)
Cyclic Glycine-Proline (cGP) is a naturally occurring cyclic dipeptide derived from the enzymatic cleavage of insulin...
MIF-1 (Pro-Leu-Gly-NH2)
MIF-1, also known as melanostatin or PLG (Pro-Leu-Gly-NH2), is a naturally occurring tripeptide first isolated from h...
FGL (FG Loop Peptide)
FGL is a synthetic pentadecapeptide corresponding to residues E681-A695 of the second fibronectin type III homology m...
Cortagen
Cortagen is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Pro, designed as a simplified bioregula...
Cerluten
Cerluten is a natural polypeptide bioregulator complex classified as Cytomax A-5 in Khavinson's peptide bioregulator ...
NA-Selank Amidate
NA-Selank Amidate is a stabilized derivative of Selank, itself a synthetic heptapeptide analog of the endogenous immu...
Beta-Endorphin
Beta-endorphin is the principal endogenous opioid peptide of the human body, first isolated and characterized by Choh...