Not medical advice. Talk to your provider before using any peptide.
Full disclaimerAnti-Aging Protocols
Peptide Schedule Research Team
Longevity protocols targeting cellular repair, telomere maintenance, and growth hormone optimization.
Anti-aging peptide protocols target several hallmarks of aging: growth hormone decline, telomere shortening, mitochondrial dysfunction, and cellular senescence.
GH secretagogue stacks (Ipamorelin + Tesamorelin or CJC-1295) restore youthful growth hormone pulsatility without the risks of exogenous HGH. Epithalon activates telomerase in 10-day pulse cycles. Newer protocols combine SS-31 for mitochondrial support with FOXO4-DRI for senescent cell clearance.
Most anti-aging protocols are long-term commitments, cycling through multiple peptides over months. Evidence ranges from FDA-approved (Tesamorelin) to preclinical (Epithalon, SS-31). Community experience fills gaps where clinical data is limited.
Epithalon + Thymosin Alpha 1
Bryan Johnson's thymus rejuvenation protocol from Project Blueprint. Epithalon (10mg/day) and Thymosin Alpha-1 (1.5mg/day) injected IM for 5 consecutive days, then nothing for 6 months. Follows the Khavinson protocol. Dosing sourced from tweets; the original post had ambiguous wording that the community later resolved. Budget $100-250 per pulse cycle.
SS-31 (Elamipretide) + Epithalon + Thymosin Alpha 1 +1
Four peptides, four aging mechanisms, 30 days. Ben Pakulski targets mitochondria with SS-31 (10mg daily), telomeres with Epithalon (5mg, 5x/week), immune function with TA-1 (1.5mg daily), and senescent cells with FOXO4-DRI (10mg EOD for 2 weeks). The FOXO4-DRI dose is 3.3x the standard aggressive tier. Budget $500-1,200 and consider starting with 1-2 peptides rather than all four simultaneously.
Epithalon + Thymosin Alpha 1
Epithalon at 5mg daily for 10 days (2x/year) as his "#1 longevity peptide," plus TA-1 at a lower-than-standard 250mcg maintenance dose (1-2x/week, daily when sick). Discussed on the Dr. Hyman Show podcast.
Epithalon + BPC-157
A biochemist's anti-aging approach: Epithalon at ~3.3-5mg/day for 20-30 days (100mg total per cycle, 2-3x/year) plus BPC-157 in two modes: 10mg monthly high-dose pulse or 250mcg daily for 2 weeks on / 6 weeks off. Tremblay owns CanLab and has 30+ years in peptide manufacturing.