Immune Peptides
Immune-modulating peptides for T-cell function, antimicrobial defense, and inflammation.
Immune peptides support your body's defense system — from T-cell production to antimicrobial activity. They're used for chronic infections, autoimmune conditions, and general immune optimization.
Thymosin Alpha-1 is the best-studied option. It's approved in over 30 countries for hepatitis B and C treatment. It enhances T-cell maturation and natural killer cell activity. KPV is an anti-inflammatory tripeptide derived from alpha-MSH that's gaining attention for gut inflammation and autoimmune support.
LL-37 takes a more direct approach — it's a human cathelicidin with antimicrobial properties. It can kill bacteria, viruses, and fungi. Most immune peptides require subcutaneous injection, though KPV can be taken orally for gut-targeted effects.
Quick Comparison
| Peptide | Route | Frequency | Half-Life | Status | Grade |
|---|---|---|---|---|---|
| Icatibant (Firazyr) | SubQ | Single dose | ~1-2 hours | FDA Approved | A |
| KPV | SubQ / Oral | Daily | ~30 min plasma | Preclinical | A |
| Romiplostim (Nplate) | SubQ | Weekly | ~3.5 days | FDA Approved | A |
| Thymosin Alpha 1 | SubQ | 2x/week | ~2 hours | Research | A |
| ACTH (Cosyntropin/Cortrosyn) | SubQ | Single dose | ~15 minutes | FDA Approved | B |
| Alpha-MSH (α-Melanocyte-Stimulating Hormone) | SubQ | Daily | ~20 minutes | Research | B |
| Bivalirudin (Angiomax) | Intravenous | Single dose | 25 minutes | FDA Approved | B |
| Enfuvirtide (Fuzeon) | SubQ | 2x Daily | ~3.8 hours | FDA Approved | B |
| Eptifibatide (Integrilin) | Intravenous | Single dose | ~2.5 hours | FDA Approved | B |
| Lactoferricin B (LfcinB) | Topical | Daily | ~2-4 hours | Research | B |
| LL-37 | SubQ | 2x/week | ~4-6 hours | Preclinical | B |
| Thymalin | SubQ | Daily | ~2-4 hours | Research | B |
| VIP (Vasoactive Intestinal Peptide) | Nasal | Daily | ~1-2 minutes | Research | B |
| Bonomarlot | Oral | Daily | Unknown | Research | C |
| Bradykinin | Intravenous / Intra-arterial | Daily | ~15-30 seconds | Research | C |
| Crystagen | Oral | Daily | ~0.5-2 hours | Research | C |
| Defensin (HNP-1) | SubQ | 3x/week | ~3-4 hours | Research | C |
| Substance P | SubQ | Daily | ~1-2 minutes | Research | C |
| Thymulin (FTS) | SubQ | 2x/week | ~10 minutes | Research | C |
| Vladonix | Oral | Daily | Unknown | Research | C |
| PNC-27 | SubQ | Daily | ~2-4 hours | Research | D |
All Immune Peptides(21)
KPV
KPV is a naturally occurring anti-inflammatory tripeptide (Lysine-Proline-Valine) derived from the C-terminal end of ...
Thymosin Alpha 1
Thymosin Alpha 1 (Tα1) is an immune-modulating peptide naturally produced by the thymus gland.
LL-37
LL-37 is the only human cathelicidin antimicrobial peptide, naturally produced by immune cells, epithelial cells, and...
Thymalin
Thymalin is a natural peptide complex isolated from calf thymus gland, developed by Vladimir Khavinson at the St.
VIP (Vasoactive Intestinal Peptide)
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide produced throughout the body, with high concentra...
Thymulin (FTS)
Thymulin, originally known as Facteur Thymique Serique (FTS) or Serum Thymic Factor, is a metallopeptide hormone prod...
PNC-27
PNC-27 is a 32-residue synthetic anticancer peptide engineered from two functional domains: the p53 transactivation d...
Crystagen
Crystagen is a synthetic tripeptide (Glu-Asp-Pro, molecular weight ~345 Da) developed through the Khavinson peptide b...
Bonomarlot
Bonomarlot is a peptide bioregulator developed at the St.
Vladonix
Vladonix is a natural thymus peptide bioregulator developed by Professor Vladimir Khavinson at the St.
Substance P
Substance P is an endogenous neuropeptide consisting of 11 amino acids (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-N...
Bradykinin
Bradykinin is a 9-amino-acid vasoactive peptide (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) generated through the enzymatic...
Alpha-MSH (α-Melanocyte-Stimulating Hormone)
Alpha-melanocyte-stimulating hormone (alpha-MSH) is a 13-amino-acid neuropeptide produced by cleavage of proopiomelan...
Defensin (HNP-1)
Human Neutrophil Peptide-1 (HNP-1) belongs to the alpha-defensin family, a class of small cationic antimicrobial pept...
Lactoferricin B (LfcinB)
Lactoferricin B is a 25-residue antimicrobial peptide (FKCRRWQWRMKKLGAPSITCVRRAF) derived from the N-terminal region ...
Icatibant (Firazyr)
Icatibant is a synthetic decapeptide containing five non-natural amino acids, designed as a highly selective competit...
Romiplostim (Nplate)
Romiplostim (Nplate) is an FDA-approved Fc-peptide fusion protein (peptibody) that acts as a thrombopoietin receptor ...
Bivalirudin (Angiomax)
Bivalirudin (brand name Angiomax) is a synthetic 20-amino-acid peptide that functions as a specific, reversible direc...
Enfuvirtide (Fuzeon)
Enfuvirtide (brand name Fuzeon) is a first-in-class 36-amino-acid synthetic peptide that represents the first member ...
Eptifibatide (Integrilin)
Eptifibatide is a synthetic cyclic heptapeptide derived from the Lys-Gly-Asp (KGD) recognition sequence of barbourin,...
ACTH (Cosyntropin/Cortrosyn)
Adrenocorticotropic hormone (ACTH) is a critical endocrine peptide synthesized and secreted by corticotroph cells in ...