CJC-1295 (No DAC) vs Ipamorelin
Side-by-side comparison of dosage, benefits, and side effects.
CJC-1295 without DAC (also called Mod GRF 1-29) is a short-acting GHRH analog that produces natural, pulsatile growth hormone release. Unlike the DAC version, it has a short half-life (~30 min), which means it stimulates a GH pulse that mimics the body's natural rhythm. It's most commonly stacked with Ipamorelin for synergistic GH release without cortisol or prolactin spikes.
View full guide →Ipamorelin is the cleanest and most selective growth hormone releasing peptide (GHRP). Unlike GHRP-6 or GHRP-2, it triggers GH release without significantly raising cortisol, prolactin, or appetite. This makes it ideal for beginners and for long-term use. Most commonly paired with CJC-1295 (No DAC) for synergistic, natural GH pulsing.
View full guide →At a Glance
| Attribute | CJC-1295 (No DAC) | Ipamorelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Half-Life | ~30 min | ~2 hours |
| Route | Subcutaneous | Subcutaneous |
| Vial Sizes | 2mg, 5mg | 2mg, 5mg |
| Beginner Dose | 100mcg Daily | 100mcg Daily |
| Moderate Dose | 100mcg 2x Daily | 200mcg 2x Daily |
| Aggressive Dose | 200mcg 2x Daily | 300mcg 3x Daily |
Key Differences
- CJC-1295 is a GHRH analog that amplifies growth hormone pulses; Ipamorelin is a GHRP that triggers GH release.
- CJC-1295 has a longer half-life (~30 min) vs Ipamorelin (~2 hours), but both are typically dosed together.
- Ipamorelin is the cleanest GHRP — no cortisol, prolactin, or hunger spikes unlike GHRP-2/6.
- They target different receptors (GHRH-R vs GHS-R) making them synergistic rather than redundant.
When to Choose CJC-1295 (No DAC)
- You want sustained GH pulse amplification
- You're looking to increase overall IGF-1 levels
- You want to pair it with a GHRP for synergy
- Sleep quality and deep sleep improvement is a priority
When to Choose Ipamorelin
- You want a clean GH secretagogue with minimal side effects
- You're concerned about cortisol or prolactin elevation
- You want to start with a single GH peptide before stacking
- Fat loss and body composition are primary goals
Can You Stack CJC-1295 (No DAC) + Ipamorelin?
CJC-1295 + Ipamorelin is the most popular GH peptide stack. They're synergistic — CJC amplifies the pulse that Ipamorelin triggers, producing a powerful, clean GH release. Available as a pre-mixed blend.