Peptide Schedule
Retatrutide35 residues (approx.)YQGTFTSDYSILDKKAQAFIEYLLEGGPSSGAPPPSEach bubble = one amino acid. Size = residue mass. Color = chemical class.Uses closest standard amino acids for non-standard residues.

Retatrutide Dosage Calculator

Weight LossInjectionPhase 2~6 days half-life

Retatrutide is the first triple-agonist peptide, targeting GLP-1, GIP, and glucagon receptors simultaneously — earning it the nickname 'Triple G.' In phase 2 trials, participants lost up to 24% of body weight at the highest dose, making it potentially the most powerful weight loss peptide ever studied.

Triple-action: GLP-1 + GIP + glucagon receptorsUp to 24% body weight loss in clinical trialsReduces liver fat significantlyImproves metabolic markers (insulin, lipids)

1mg · Weekly

100500
40.0 units
100 units (1mL)
Concentration
2,500
mcg/mL
Draw Volume
0.400
mL
Syringe Units
40.0
units
Doses / Vial
5
doses

Summary: Add 2mL BAC water to your 5mg vial. Draw to 40.0 units on a U-100 syringe for a 1mg dose. This vial will last 5 doses.

Cycle Planner

Subcutaneous. Typical beginner frequency: weekly.

Retatrutide Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~6 days
50%25%12.5%100%75%50%25%0%06d12d18d24d30dTime after injectionDose remaining
After 1 half-life (6d): 50% remainsAfter 2 half-lives (12d): 25% remainsAfter 3 half-lives (18d): 12.5% remains
At a 4mg dose: 50% = 2.0mg remaining after 6d. Recommended frequency: Weekly.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

Retatrutide Dosing Protocol

LevelDose / InjectionFrequency
Beginner1mgWeekly
Moderate4mgWeekly
Aggressive8mgWeekly

Note: Triple-agonist: GLP-1 + GIP + glucagon. Up to 24% body weight loss in trials. Titrate from 1mg weekly over 12+ weeks. Also improves liver fat and metabolic markers.

About Retatrutide

Retatrutide is the first triple-agonist peptide, targeting GLP-1, GIP, and glucagon receptors simultaneously — earning it the nickname 'Triple G.' In phase 2 trials, participants lost up to 24% of body weight at the highest dose, making it potentially the most powerful weight loss peptide ever studied. The glucagon component adds direct fat-burning and liver fat reduction beyond what GLP-1 alone achieves.

Frequently Asked Questions