Retatrutide Dosage Calculator
Retatrutide is the first triple-agonist peptide, targeting GLP-1, GIP, and glucagon receptors simultaneously — earning it the nickname 'Triple G.' In phase 2 trials, participants lost up to 24% of body weight at the highest dose, making it potentially the most powerful weight loss peptide ever studied.
1mg · Weekly
Summary: Add 2mL BAC water to your 5mg vial. Draw to 40.0 units on a U-100 syringe for a 1mg dose. This vial will last 5 doses.
Cycle Planner
Retatrutide Pharmacokinetics
Pharmacokinetics — Active Dose Over Time
t½ = ~6 daysDisclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Retatrutide Dosing Protocol
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 1mg | Weekly |
| Moderate | 4mg | Weekly |
| Aggressive | 8mg | Weekly |
Note: Triple-agonist: GLP-1 + GIP + glucagon. Up to 24% body weight loss in trials. Titrate from 1mg weekly over 12+ weeks. Also improves liver fat and metabolic markers.
About Retatrutide
Retatrutide is the first triple-agonist peptide, targeting GLP-1, GIP, and glucagon receptors simultaneously — earning it the nickname 'Triple G.' In phase 2 trials, participants lost up to 24% of body weight at the highest dose, making it potentially the most powerful weight loss peptide ever studied. The glucagon component adds direct fat-burning and liver fat reduction beyond what GLP-1 alone achieves.