How many units of IGF-1 DES should I draw?

It depends on your vial size, BAC water, and dose. For a 0.1mg vial with 1mL BAC water, a beginner dose of 50mcg is typically 50 units on a U-100 syringe. Use the calculator above for your exact numbers.

How much BAC water should I add to IGF-1 DES?

The standard amount is 1mL of bacteriostatic water for a 0.1mg vial. More water gives a more dilute solution — easier to measure small doses. Less water means fewer injections per vial. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

How long does a IGF-1 DES vial last?

At a beginner dose of 50mcg daily, a 0.1mg vial lasts about 2 doses. The calculator shows exact doses per vial for your selected tier.

What syringe should I use for IGF-1 DES?

Most people use a U-100 insulin syringe (1mL / 100 units). For very small doses, a U-50 or U-30 syringe gives better precision. The calculator adjusts units automatically for whichever syringe you pick.

IGF-1 DES Dosage Calculator

Growth HormoneInjectionResearch~20-30 minutes half-life

IGF-1 DES (des(1-3) Insulin-like Growth Factor-1) is a 67-amino acid truncated analog of IGF-1, missing the first three N-terminal amino acids (Gly-Pro-Glu).

Site-specific muscle growth when injected locally post-workoutApproximately 10x more potent than native IGF-1Promotes muscle hyperplasia (new muscle fiber creation)Short half-life limits prolonged systemic exposure4 weeks on / 4 weeks off

Vial Size

BAC Water (mL)

Dosing Level

50mcg · Daily

Custom Dose (mcg) — optional

Syringe Type

50.0 units

100 units (1mL)

Concentration

100

mcg/mL

Draw Volume

0.500

Syringe Units

50.0

units

Doses / Vial

doses

Summary: Add 1mL BAC water to your 0.1mg vial. Draw to 50.0 units on a U-100 syringe for a 50mcg dose. This vial will last 2 doses.

Cycle Planner

Cycle Length (weeks)

Price Per Vial ($) — optional

Intramuscular (preferred) or Subcutaneous. Typical beginner frequency: daily.

IGF-1 DES Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~20-30 minutes

After 1 half-life (25m): 50% remainsAfter 2 half-lives (50m): 25% remainsAfter 3 half-lives (1h): 12.5% remains

At a 80mcg dose: 50% = 40mcg remaining after 25m. Recommended frequency: Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

IGF-1 DES Dosing Protocol

Level	Dose / Injection	Frequency
Beginner	50mcg	Daily
Moderate	80mcg	Daily
Aggressive	120mcg	Daily

Note: Truncated IGF-1 analog missing first 3 amino acids (des(1-3)IGF-1). Does not bind IGF binding proteins, giving it ~10x greater potency than native IGF-1 but a very short half-life. Inject intramuscularly into the target muscle immediately post-workout for site-specific growth. Use insulin syringes for accurate dosing. Monitor blood sugar closely.

About IGF-1 DES

IGF-1 DES (des(1-3) Insulin-like Growth Factor-1) is a 67-amino acid truncated analog of IGF-1, missing the first three N-terminal amino acids (Gly-Pro-Glu). This structural modification eliminates binding to all six IGF binding proteins (IGFBPs), meaning the entire dose remains bioactive in free form. The result is roughly 10-fold greater potency than native IGF-1, but with a half-life of only 20-30 minutes. This rapid clearance makes IGF-1 DES uniquely suited for localized intramuscular injection, allowing site-specific muscle hypertrophy and hyperplasia without prolonged systemic IGF-1 elevation. It activates the IGF-1 receptor (IGF-1R) and downstream PI3K/Akt/mTOR and MAPK/ERK signaling to drive protein synthesis, satellite cell proliferation, and new muscle fiber formation.

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