Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20266 Citations
IGF-1 DES67 residuesTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSAEach bubble = one amino acid. Size = residue mass. Color = chemical class.Turns your vial size, BAC water, and dose into exact syringe units. Free, no signup.
Adjust vial, water, and dose — answer updates live
All three take the same units for the same dose. A smaller barrel just spreads it over more space.
on a U-100 syringe for a 50mcg dose
Add 1 mL BAC water to your 0.1 mg vial. Draw to 50.0 units on a U-100 syringe for a 50mcg dose. This vial will last 2 doses.
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Never miss a dose — 50mcg training days only (4-5x/week), draw 50.0 units on U-100 syringe.
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IGF-1 DES delivers roughly 10x the receptor potency of native IGF-1 by skipping binding protein attachment entirely. A 20-to-30-minute half-life makes post-workout intramuscular injection non-negotiable. Community results point to visible localized growth by week 3, but hypoglycemia management is the price of entry.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 50mcg | Training days only (4-5x/week) |
| Moderate | 80mcg | Training days only (4-5x/week) |
| Aggressive | 120mcg | Training days only (4-5x/week) |
Reconstitution math for the two common vial sizes. For a 0.1 mg (100 mcg) vial: add 1 mL bacteriostatic water. Concentration becomes 100 mcg/mL. A 50 mcg dose is 50 units on a U-100 insulin syringe. For a 1 mg vial: add 2 mL bacteriostatic water. Concentration becomes 500 mcg/mL. A 50 mcg dose is 10 units; 80 mcg is 16 units; 100 mcg is 20 units on a U-100 syringe. Timing is everything with DES. You have a 10-to-15-minute window after finishing the target muscle group to get the injection done. Prep your syringe before your last working set so you're ready. The ultra-short half-life means delays past 15 minutes post-workout significantly reduce local receptor exposure. Vendor quality is a real concern. The research-chemical market for DES has documented purity inconsistencies. Get a Certificate of Analysis from Janoshik or Colmaric before committing to a vial. Start with a low test dose (20 to 30 mcg) to assess your blood glucose response before running a full protocol.
Dosing based on Community dosing consensus from peptide research communities — 9 published references.View all sources →
Based on a 0.1mg vial, 1mL of bacteriostatic water, the beginner dose (50mcg), and a U-100 syringe. Change any input in the calculator and every line moves with it.
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Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
