Retatrutide (Triple G) Titration Protocol
Triple agonist (GLP-1/GIP/Glucagon). Titrate slowly — up to 24% weight loss in clinical trials.
| Phase | Weeks | Dose | Frequency |
|---|---|---|---|
| Initiation | 1–4 | 1mg | Weekly |
| Titration 1 | 5–8 | 2mg | Weekly |
| Titration 2 | 9–12 | 4mg | Weekly |
| Titration 3 | 13–16 | 8mg | Weekly |
| Maintenance | Week 17+ | 12mg | Weekly |