Peptide ScheduleGHRP-2 vs GHRP-6
Side-by-side comparison of dosage, benefits, and side effects.
GHRP-2 (Growth Hormone Releasing Peptide-2) is a second-generation GH secretagogue that stimulates the pituitary gland via the ghrelin receptor. It produces a stronger GH pulse than Ipamorelin but with fewer side effects than GHRP-6. It causes a moderate increase in appetite (less than GHRP-6) and slight elevations in cortisol and prolactin. It's widely used in research and clinical settings as a reliable GH-releasing agent.
View full guide →GHRP-6 (Growth Hormone Releasing Peptide-6) is one of the most potent GH secretagogues available. It works by mimicking ghrelin, the hunger hormone, which triggers a strong growth hormone pulse from the pituitary. Unlike Ipamorelin, GHRP-6 significantly increases appetite and raises cortisol and prolactin slightly. This makes it ideal for mass-gaining protocols where increased caloric intake is desired.
View full guide →At a Glance
| Attribute | GHRP-2 | GHRP-6 |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Half-Life | ~15-30 min | ~20 min |
| Route | Subcutaneous | Subcutaneous |
| Vial Sizes | 5mg | 5mg |
| Beginner Dose | 100mcg Daily | 100mcg Daily |
| Moderate Dose | 200mcg 2x Daily | 200mcg 2x Daily |
| Aggressive Dose | 300mcg 3x Daily | 300mcg 3x Daily |
Key Differences
- GHRP-2 produces stronger GH release per dose; GHRP-6 causes more appetite stimulation via ghrelin.
- GHRP-6 raises cortisol and prolactin more than GHRP-2.
- GHRP-2 is preferred when hunger side effects are unwanted; GHRP-6 is preferred when appetite stimulation is desired.
- Both have similar half-lives and dosing frequencies.
When to Choose GHRP-2
- You want maximum GH release with fewer side effects
- Appetite stimulation is unwanted (cutting/weight loss phases)
- You want to minimize cortisol and prolactin elevation
- Clean GH release is the priority
When to Choose GHRP-6
- You want appetite stimulation (bulking/gaining weight)
- Enhanced hunger signaling is a desired benefit
- You're in a mass-gain or recovery phase
- Cost is a factor (GHRP-6 is often cheaper)
Can You Stack GHRP-2 + GHRP-6?
GHRP-2 and GHRP-6 target the same receptor (GHS-R). Stack either one with CJC-1295 instead for synergy.