Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 202613 Citations
Tesamorelin is the only FDA-approved GHRH analog for visceral fat reduction, backed by Phase 3 data in 816 patients. Originally indicated for HIV lipodystrophy, it's now widely used off-label for belly fat and GH optimization. Antibody formation after extended use is the main drawback.
2mg · Daily
Summary: Add 2mL BAC water to your 2mg vial. Draw to 200.0 units on a U-100 syringe for a 2mg dose. This vial will last 1 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 2mg | Daily |
| Moderate | 2mg | Daily |
| Aggressive | 2mg | Daily |
With a 5 mg vial and 2 mL bacteriostatic water, you get 2.5 mg/mL (2500 mcg/mL). At that concentration: 2000 mcg (the standard dose) is 80 units on a U-100 insulin syringe. That's 0.8 mL, so you'll use close to half the syringe. Each 5 mg vial gives you 2.5 daily doses at 2 mg per day. With a 2 mg vial and 2 mL BAC water, you get 1 mg/mL. A full 2 mg dose requires the entire reconstituted vial in one shot. Not practical for multi-day use; the 5 mg vial is the better choice. Inject into abdominal subcutaneous fat only. The FDA label specifies this, and the clinical data was collected this way. Don't rotate to thigh or arm. Rotate within the abdomen, at least 2 cm from the umbilicus. The non-obvious thing: your IGF-1 check at four to six weeks isn't optional. If IGF-1 hasn't risen, either the peptide is degraded, your injection technique is off, or you've drawn a bad batch from the compounder. Don't run a full 26-week cycle without confirming the molecule is actually working. Pre-bed injection is the community preference for off-label use because it matches the natural nocturnal GH surge. FDA trials used morning dosing. Either works; consistency matters more than timing.
Dosing based on Egrifta FDA Prescribing Information (2025) — 18 published references.View all sources →
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Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Tesamorelin is the only FDA-approved GHRH analog for visceral fat reduction, backed by Phase 3 data in 816 patients. Originally indicated for HIV lipodystrophy, it's now widely used off-label for belly fat and GH optimization. Antibody formation after extended use is the main drawback.