How many units of Substance P should I draw?

It depends on your vial size, BAC water, and dose. For a 2mg vial with 2mL BAC water, a beginner dose of 50mcg is typically 5 units on a U-100 syringe. Use the calculator above for your exact numbers.

How much BAC water should I add to Substance P?

The standard amount is 2mL of bacteriostatic water for a 2mg vial. More water gives a more dilute solution — easier to measure small doses. Less water means fewer injections per vial. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

How long does a Substance P vial last?

At a beginner dose of 50mcg daily, a 2mg vial lasts about 40 doses. The calculator shows exact doses per vial for your selected tier.

What syringe should I use for Substance P?

Most people use a U-100 insulin syringe (1mL / 100 units). For very small doses, a U-50 or U-30 syringe gives better precision. The calculator adjusts units automatically for whichever syringe you pick.

Substance P Dosage Calculator

ImmuneInjectionResearch~1-2 minutes half-life

Substance P is an endogenous neuropeptide consisting of 11 amino acids (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2) belonging to the tachykinin peptide family.

Promotes wound healing and tissue repair via keratinocyte and fibroblast stimulationEnhances immune cell mobilization and activation (macrophages, T-cells, mast cells)Stimulates angiogenesis to support tissue regenerationModulates neurogenic inflammation for immune defense signaling4 weeks on / 4 weeks off

Vial Size

BAC Water (mL)

Dosing Level

50mcg · Daily

Custom Dose (mcg) — optional

Syringe Type

5.0 units

100 units (1mL)

Concentration

1,000

mcg/mL

Draw Volume

0.050

Syringe Units

5.0

units

Doses / Vial

doses

Summary: Add 2mL BAC water to your 2mg vial. Draw to 5.0 units on a U-100 syringe for a 50mcg dose. This vial will last 40 doses.

Cycle Planner

Cycle Length (weeks)

Price Per Vial ($) — optional

Subcutaneous / Intravenous (research settings). Typical beginner frequency: daily.

Substance P Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~1-2 minutes (rapid enzymatic degradation)

After 1 half-life (2m): 50% remainsAfter 2 half-lives (3m): 25% remainsAfter 3 half-lives (5m): 12.5% remains

At a 100mcg dose: 50% = 50mcg remaining after 2m. Recommended frequency: Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

Substance P Dosing Protocol

Level	Dose / Injection	Frequency
Beginner	50mcg	Daily
Moderate	100mcg	Daily
Aggressive	200mcg	Daily

Note: Endogenous 11-amino-acid neuropeptide (RPKPQQFFGLM-NH2) of the tachykinin family. Primarily involved in pain signaling (nociception), neurogenic inflammation, and immune modulation via the NK1 receptor. Extremely short half-life limits direct therapeutic use — most clinical strategies target its receptor (NK1R) with antagonists rather than administering Substance P itself. Research use only.

About Substance P

Substance P is an endogenous neuropeptide consisting of 11 amino acids (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2) belonging to the tachykinin peptide family. Discovered in 1931, it is one of the most extensively studied neuropeptides in biomedical research. Substance P is widely distributed throughout the central and peripheral nervous systems and acts as a key neurotransmitter and neuromodulator. It signals primarily through the neurokinin-1 (NK1) receptor, mediating pain transmission, neurogenic inflammation, immune cell activation, and wound healing. Its dual role in both pro-inflammatory signaling and tissue repair makes it a critical molecule in understanding pain, inflammation, and immune responses.

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