Peptide Schedule
PTD-DBM15 residues (approx.)RRRRRRRRYKQFRDHEach bubble = one amino acid. Size = residue mass. Color = chemical class.Uses closest standard amino acids for non-standard residues.

PTD-DBM Dosage Calculator

Anti-AgingTopicalResearch~2-4 hours half-life

PTD-DBM (Protein Transduction Domain-fused Dishevelled Binding Motif) is a synthetic peptide developed at Yonsei University that activates the Wnt/β-catenin signaling pathway by competitively disrupting the binding between CXXC5 and Dishevelled (Dvl).

Activates Wnt/β-catenin pathway to promote hair follicle regenerationStimulates wound-induced hair neogenesis (WIHN)Counteracts DHT-induced hair loss mediated by PGD2 and CXXC5Non-invasive topical application — no injections required12 weeks on / 4 weeks off

500mcg · Weekly

100500
0.0 units
100 units (1mL)
Concentration
0
mcg/mL
Draw Volume
< 0.001
mL
Syringe Units
< 0.1
units
Doses / Vial
0
doses

Summary: Add 0mL BAC water to your 5mg vial. Draw to < 0.1 units on a U-100 syringe for a 500mcg dose. This vial will last 0 doses.

Cycle Planner

Topical (scalp spray or serum). Typical beginner frequency: weekly.

PTD-DBM Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~2-4 hours (estimated, topical peptide)
50%25%12.5%100%75%50%25%0%03h6h9h12h15hTime after injectionDose remaining
After 1 half-life (3h): 50% remainsAfter 2 half-lives (6h): 25% remainsAfter 3 half-lives (9h): 12.5% remains
At a 1mg dose: 50% = 500mcg remaining after 3h. Recommended frequency: Weekly.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

PTD-DBM Dosing Protocol

LevelDose / InjectionFrequency
Beginner500mcgWeekly
Moderate1mgWeekly
Aggressive1mg2x/week

Note: Topical peptide targeting CXXC5-Dvl interaction. Applied as scalp spray or serum. Often combined with valproic acid and microneedling for synergistic effect. No injection required — topical application only.

About PTD-DBM

PTD-DBM (Protein Transduction Domain-fused Dishevelled Binding Motif) is a synthetic peptide developed at Yonsei University that activates the Wnt/β-catenin signaling pathway by competitively disrupting the binding between CXXC5 and Dishevelled (Dvl). CXXC5 is a zinc finger protein overexpressed in balding scalps that acts as a negative regulator of hair follicle regeneration. By blocking this interaction, PTD-DBM restores Wnt signaling, promoting hair regrowth and wound-induced hair follicle neogenesis. In animal studies, topical PTD-DBM combined with valproic acid produced significant new follicle formation within 28 days.

Frequently Asked Questions