Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20268 Citations
HCG (Human Chorionic Gonadotropin)19 residues (approx.)CPTMTRVLQGVLPALQVVCEach bubble = one amino acid. Size = residue mass. Color = chemical class.Uses closest standard amino acids for non-standard residues.HCG mimics luteinizing hormone and is the most evidence-backed option for preserving fertility and testicular volume during TRT. The Coviello 2005 dose-response trial confirmed that low doses maintain intratesticular testosterone, though brand-name pricing after the 2020 compounding ban remains a real barrier.
250mcg · EOD
Summary: Add 2mL BAC water to your 5000mg vial. Draw to < 0.1 units on a U-100 syringe for a 250mcg dose. This vial will last 20000 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 250 IU | EOD |
| Moderate | 500 IU | EOD |
| Aggressive | 1,000 IU | 3x/week |
Reconstitution math for a 5,000 IU vial with 2 mL bacteriostatic water: you get 2,500 IU per mL, or 250 IU per 10 units on a standard 100-unit insulin syringe. For 500 IU, draw to the 20-unit mark. For 1,500 IU (PCT dosing), that's 60 units. Always use bacteriostatic water, not sterile water. Multi-dose vials need the benzyl alcohol preservative. Sterile water accelerates degradation fast after reconstitution. Store reconstituted HCG refrigerated at 2 to 8 degrees Celsius and use within 60 days per the Pregnyl label. Lyophilized powder keeps at room temperature for up to 60 days or refrigerated for up to 2 years. The thing most beginners miss: brand-name HCG is the only legal option in the US since March 2020. If a telehealth clinic offers "compounded HCG," that product is federally illegal. GoodRx coupons bring Pregnyl 10,000 IU down to roughly $289 at major pharmacy chains. Check the NDC number on your vial to confirm it matches the Organon or Ferring product.
Dosing based on Pregnyl (chorionic gonadotropin) FDA Prescribing Information (2023) — 13 published references.View all sources →
Cross-check your HCG (Human Chorionic Gonadotropin) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
HCG mimics luteinizing hormone and is the most evidence-backed option for preserving fertility and testicular volume during TRT. The Coviello 2005 dose-response trial confirmed that low doses maintain intratesticular testosterone, though brand-name pricing after the 2020 compounding ban remains a real barrier.
