How many units of HCG (Human Chorionic Gonadotropin) should I draw?

It depends on your vial size, BAC water, and dose. For a 5000IU vial with 2mL BAC water, a beginner dose of 250IU is typically 0 units on a U-100 syringe. Use the calculator above for your exact numbers.

How much BAC water should I add to HCG (Human Chorionic Gonadotropin)?

The standard amount is 2mL of bacteriostatic water for a 5000IU vial. More water gives a more dilute solution — easier to measure small doses. Less water means fewer injections per vial. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

How long does a HCG (Human Chorionic Gonadotropin) vial last?

At a beginner dose of 250IU 3x/week, a 5000IU vial lasts about 20000 doses. The calculator shows exact doses per vial for your selected tier.

What syringe should I use for HCG (Human Chorionic Gonadotropin)?

Most people use a U-100 insulin syringe (1mL / 100 units). For very small doses, a U-50 or U-30 syringe gives better precision. The calculator adjusts units automatically for whichever syringe you pick.

HCG (Human Chorionic Gonadotropin) Dosage Calculator

Sexual HealthInjectionFDA Approved~33 hours half-life

HCG isn't technically a peptide — it's a glycoprotein hormone produced naturally during pregnancy.

Preserves fertility and sperm production during TRTPrevents testicular atrophy from exogenous testosteroneMaintains intratesticular testosterone at physiologic levelsFDA-approved with decades of clinical use data

Vial Size

BAC Water (mL)

Dosing Level

250mcg · 3x/week

Custom Dose (mcg) — optional

Syringe Type

0.0 units

100 units (1mL)

Concentration

2,500,000

mcg/mL

Draw Volume

< 0.001

Syringe Units

< 0.1

units

Doses / Vial

20000

doses

Very small draw (< 0.1 units) — difficult to measure accurately. Consider using less BAC water for a more concentrated solution.

Try 0.5mL BAC water for an easier-to-measure draw.

Summary: Add 2mL BAC water to your 5000mg vial. Draw to < 0.1 units on a U-100 syringe for a 250mcg dose. This vial will last 20000 doses.

Cycle Planner

Cycle Length (weeks)

Price Per Vial ($) — optional

Subcutaneous or Intramuscular. Typical beginner frequency: 3x/week.

HCG (Human Chorionic Gonadotropin) Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~33 hours

After 1 half-life (33h): 50% remainsAfter 2 half-lives (3d): 25% remainsAfter 3 half-lives (4d): 12.5% remains

At a 500mcg dose: 50% = 250mcg remaining after 33h. Recommended frequency: 3x/week.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

HCG (Human Chorionic Gonadotropin) Dosing Protocol

Level	Dose / Injection	Frequency
Beginner	250 IU	3x/week
Moderate	500 IU	3x/week
Aggressive	1,000 IU	3x/week

Note: IMPORTANT: Doses shown are in IU, not mcg. Vial sizes represent 5,000 IU and 10,000 IU. Since March 2020, compounding pharmacies can no longer produce HCG — only brand-name versions (Pregnyl, Novarel, Ovidrel) are available. Use bacteriostatic water for reconstitution.

About HCG (Human Chorionic Gonadotropin)

HCG isn't technically a peptide — it's a glycoprotein hormone produced naturally during pregnancy. But it's become one of the most widely used compounds in TRT and fertility protocols because it mimics luteinizing hormone (LH). When men take exogenous testosterone, the brain stops sending LH signals to the testes, which causes them to shrink and stop producing sperm. HCG fills that gap — it keeps the testes functioning, preserves fertility, and maintains intratesticular testosterone production even while on TRT. The FDA approved HCG decades ago for fertility indications under brand names like Pregnyl, Novarel, and Ovidrel. However, in March 2020, the FDA reclassified HCG as a biologic under the BPCIA, which pulled it from compounding pharmacy shelves overnight. Today, only brand-name pharmaceutical HCG is legally available in the US — a change that significantly increased costs for TRT patients. A key study by Coviello et al. (2005) showed that just 250 IU of HCG every other day was enough to maintain intratesticular testosterone at 25% of baseline in men on exogenous testosterone — compared to near-zero without it. At 500 IU every other day, intratesticular testosterone was maintained at about 7x higher than the suppressed group.

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