Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20265 Citations
DNSP-1111 residuesPPEAPAEDRSLEach bubble = one amino acid. Size = residue mass. Color = chemical class.Turns your vial size, BAC water, and dose into exact syringe units. Free, no signup.
Adjust vial, water, and dose — answer updates live
All three take the same units for the same dose. A smaller barrel just spreads it over more space.
on a U-100 syringe for a 100mcg dose
Add 2 mL BAC water to your 5 mg vial. Draw to 4.0 units on a U-100 syringe for a 100mcg dose. This vial will last 50 doses.
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Never miss a dose — 100mcg daily, draw 4.0 units on U-100 syringe.
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DNSP-11 is a GDNF-derived 11-amino-acid peptide that doubled dopamine levels in rat substantia nigra from a single injection. Intranasal delivery confirmed brain penetration within 30 minutes. Zero human trials exist; all data comes from rodent and primate studies at one academic lab.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 100mcg | Daily |
| Moderate | 300mcg | Daily |
| Aggressive | 300mcg | Daily |
Reconstitution math first. A 10 mg vial with 2 mL bacteriostatic water gives you 5 mg/mL, or 5 mcg per microliter. For the 300 mcg target dose, you'll draw 60 microliters total (6 units on an insulin syringe) into a nasal atomizer device, split across both nostrils. With a 5 mg vial and 2 mL BAC water, concentration is 2.5 mg/mL. The 300 mcg dose becomes 120 microliters (12 units). That's a larger nasal volume; some users prefer the 10 mg vial for tighter delivery. The non-obvious thing: standard insulin syringe markings are too coarse for reliable 60 microliter accuracy. You'll want a precision nasal atomizer (MAD Nasal or equivalent) that can meter small volumes. A 10 microliter pipetting error at 300 mcg represents a 3.3% dose deviation. Don't confuse the 28-day effect duration with dosing frequency. That 28-day number came from a direct surgical injection into the substantia nigra, not intranasal delivery. Daily intranasal dosing is still the protocol. Verify C-terminal amidation (-NH2) on your supplier's CoA. The correct sequence is PPEAPAEDRSL-NH2 with MW 1210.33 Da. Non-amidated product has different biological activity.
Dosing based on Very limited human data: dose based on preclinical research — 10 published references.View all sources →
Based on a 5mg vial, 2mL of bacteriostatic water, the beginner dose (100mcg), and a U-100 syringe. Change any input in the calculator and every line moves with it.
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Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
