Peptide Schedule
AHK-Cu3 residuesAHKEach bubble = one amino acid. Size = residue mass. Color = chemical class.AHK-Cu Dosage Calculator
AHK-Cu (Copper Tripeptide-3) is a synthetic copper-binding peptide composed of alanine, histidine, and lysine chelated to a copper ion (Cu2+).
100mcg · Daily
Summary: Add 2mL BAC water to your 5mg vial. Draw to 4.0 units on a U-100 syringe for a 100mcg dose. This vial will last 50 doses.
Cycle Planner
AHK-Cu Pharmacokinetics
Pharmacokinetics — Active Dose Over Time
t½ = ~1-2 hours (estimated)Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
AHK-Cu Dosing Protocol
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 100mcg | Daily |
| Moderate | 250mcg | Daily |
| Aggressive | 500mcg | Daily |
Note: Synthetic copper tripeptide (Ala-His-Lys-Cu). Primarily studied for hair follicle stimulation and skin rejuvenation. Available as injectable or topical. Closely related to GHK-Cu but with a different amino acid at position 1. Topical concentrations typically 0.5-1%.
About AHK-Cu
AHK-Cu (Copper Tripeptide-3) is a synthetic copper-binding peptide composed of alanine, histidine, and lysine chelated to a copper ion (Cu2+). It shares structural similarities with GHK-Cu but replaces the first-position glycine with alanine, which changes its three-dimensional conformation and receptor interactions. Research suggests AHK-Cu is particularly effective at stimulating dermal papilla cells and extending the anagen (active growth) phase of hair follicles. A 2007 study in the Archives of Dermatological Research demonstrated that AHK-Cu at concentrations as low as 10^-12 molar could stimulate hair follicle elongation and increase VEGF expression in human dermal papilla cells in vitro. Beyond hair, AHK-Cu activates fibroblast proliferation and promotes collagen and elastin synthesis, supporting firmer and smoother skin over time. The peptide modulates the Bcl-2/Bax ratio in dermal cells, providing anti-apoptotic protection that helps maintain cell viability during aging and stress. It also reduces levels of cleaved caspase-3 and PARP, two execution enzymes in the programmed cell death cascade. While GHK-Cu remains the more extensively studied copper peptide with broad gene-modulating effects, AHK-Cu offers a more targeted profile with particular strength in hair follicle biology and localized skin repair. Both injectable and topical formulations exist, though topical delivery at 0.5-1% concentration is the most common research application. AHK-Cu is considered a research compound with limited human clinical data, and users should approach it with appropriate caution.