Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20267 Citations
SNAP-89 residuesEEEMQRRADEach bubble = one amino acid. Size = residue mass. Color = chemical class.SNAP-8 competes with native SNAP-25 at the SNARE complex to reduce muscle-driven wrinkle depth. Manufacturer data reports 35% average reduction over 28 days. Independent replication is missing, but community users confirm subtle softening of expression lines with 8 to 12 weeks of consistent topical use.
100mcg · Daily
Summary: Add 0mL BAC water to your 5mg vial. Draw to < 0.1 units on a U-100 syringe for a 100mcg dose. This vial will last 0 doses.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 100mcg | Daily |
| Moderate | 250mcg | Daily |
| Aggressive | 500mcg | Daily |
SNAP-8 is a topical peptide. There is no vial to reconstitute with bacteriostatic water. Instead, you are formulating a serum. The standard source material is Lotioncrafter SNAP-8 Solution C, which contains 0.05% active peptide. When you add this at 10% use rate into your serum base, your finished product contains 0.005% actual SNAP-8 peptide. At 5% use rate, you get 0.0025% active. At 3%, you get 0.0015% active. Most beginners start at 3 to 5% use rate and work up. The manufacturer's efficacy studies used 10% of their solution. Lotioncrafter sells the solution at $18.85 for 8g, $52.75 for 30g, or $83.95 for 60g. The thing most people miss: commercial SNAP-8 products that list the peptide near the bottom of their ingredient list contain negligible concentrations. You cannot judge dose adequacy from the front-of-label marketing claim. Ingredient list position is your only proxy without HPLC testing. Store your finished serum at 2 to 8 degrees Celsius in an airless pump bottle. Heat and UV break down peptide integrity faster than you would expect.
Dosing based on Cosmeceutical industry standard concentrations — 8 published references.View all sources →
Cross-check your SNAP-8 reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
SNAP-8 competes with native SNAP-25 at the SNARE complex to reduce muscle-driven wrinkle depth. Manufacturer data reports 35% average reduction over 28 days. Independent replication is missing, but community users confirm subtle softening of expression lines with 8 to 12 weeks of consistent topical use.
