PEG-MGF Dosage Calculator
PEG-MGF (Pegylated Mechano Growth Factor) is the PEGylated form of MGF, a splice variant of IGF-1 (specifically IGF-1Ec) produced in response to mechanical loading of muscle tissue.
150mcg · 2x/week
Summary: Add 1mL BAC water to your 2mg vial. Draw to 7.5 units on a U-100 syringe for a 150mcg dose. This vial will last 13 doses.
Cycle Planner
PEG-MGF Pharmacokinetics
Pharmacokinetics — Active Dose Over Time
t½ = ~48-72 hours (PEGylated); native MGF: ~5-7 minutesDisclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
PEG-MGF Dosing Protocol
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 150mcg | 2x/week |
| Moderate | 200mcg | 3x/week |
| Aggressive | 400mcg | 3x/week |
Note: PEGylated form of Mechano Growth Factor (IGF-1Ec splice variant). The PEG moiety extends half-life from minutes to days. Inject post-workout near the trained muscle for localized effects. Do not combine with IGF-1 LR3 in the same injection window — stagger by several hours.
About PEG-MGF
PEG-MGF (Pegylated Mechano Growth Factor) is the PEGylated form of MGF, a splice variant of IGF-1 (specifically IGF-1Ec) produced in response to mechanical loading of muscle tissue. Native MGF has an extremely short half-life of approximately 5-7 minutes, making it impractical for therapeutic use. The addition of a polyethylene glycol (PEG) chain shields the peptide from enzymatic degradation and renal clearance, extending its half-life to approximately 48-72 hours. PEG-MGF activates quiescent muscle satellite (stem) cells, promoting their proliferation without triggering premature differentiation — a critical distinction from other growth factors like IGF-1 LR3, which primarily drives differentiation. This makes PEG-MGF a targeted tool for muscle repair and hypertrophy in preclinical research.