Peptide Schedule
PEG-MGF24 residuesYQPPSTNKNTKSQRRKGSTFEERKEach bubble = one amino acid. Size = residue mass. Color = chemical class.

PEG-MGF Dosage Calculator

Growth HormoneInjectionResearch~48-72 hours half-life

PEG-MGF (Pegylated Mechano Growth Factor) is the PEGylated form of MGF, a splice variant of IGF-1 (specifically IGF-1Ec) produced in response to mechanical loading of muscle tissue.

Activates muscle satellite (stem) cells for repair and growthExtended half-life (48-72 hours) vs minutes for native MGFPromotes muscle fiber regeneration and hypertrophySupports recovery from exercise-induced muscle damage6 weeks on / 4 weeks off

150mcg · 2x/week

100500
7.5 units
100 units (1mL)
Concentration
2,000
mcg/mL
Draw Volume
0.075
mL
Syringe Units
7.5
units
Doses / Vial
13
doses

Summary: Add 1mL BAC water to your 2mg vial. Draw to 7.5 units on a U-100 syringe for a 150mcg dose. This vial will last 13 doses.

Cycle Planner

Subcutaneous or Intramuscular (site-specific). Typical beginner frequency: 2x/week.

PEG-MGF Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~48-72 hours (PEGylated); native MGF: ~5-7 minutes
50%25%12.5%100%75%50%25%0%03d5d8d10d13dTime after injectionDose remaining
After 1 half-life (3d): 50% remainsAfter 2 half-lives (5d): 25% remainsAfter 3 half-lives (8d): 12.5% remains
At a 200mcg dose: 50% = 100mcg remaining after 3d. Recommended frequency: 3x/week.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

PEG-MGF Dosing Protocol

LevelDose / InjectionFrequency
Beginner150mcg2x/week
Moderate200mcg3x/week
Aggressive400mcg3x/week

Note: PEGylated form of Mechano Growth Factor (IGF-1Ec splice variant). The PEG moiety extends half-life from minutes to days. Inject post-workout near the trained muscle for localized effects. Do not combine with IGF-1 LR3 in the same injection window — stagger by several hours.

About PEG-MGF

PEG-MGF (Pegylated Mechano Growth Factor) is the PEGylated form of MGF, a splice variant of IGF-1 (specifically IGF-1Ec) produced in response to mechanical loading of muscle tissue. Native MGF has an extremely short half-life of approximately 5-7 minutes, making it impractical for therapeutic use. The addition of a polyethylene glycol (PEG) chain shields the peptide from enzymatic degradation and renal clearance, extending its half-life to approximately 48-72 hours. PEG-MGF activates quiescent muscle satellite (stem) cells, promoting their proliferation without triggering premature differentiation — a critical distinction from other growth factors like IGF-1 LR3, which primarily drives differentiation. This makes PEG-MGF a targeted tool for muscle repair and hypertrophy in preclinical research.

Frequently Asked Questions