Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20265 Citations
Gonadorelin is the synthetic form of GnRH, FDA-approved since 1978. Used alongside TRT to preserve testicular function and fertility. Dosing frequency matters more than dose size; its 2 to 40 minute half-life makes protocol design the key deciding factor.
100mcg · 2x/week
Summary: Add 2mL BAC water to your 2mg vial. Draw to 10.0 units on a U-100 syringe for a 100mcg dose. This vial will last 20 doses.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 100mcg | 2x/week |
| Moderate | 200mcg | 2x/week |
| Aggressive | 200mcg | 3x/week |
Reconstitution math: a 2 mg vial plus 2 mL bacteriostatic water gives you 1,000 mcg/mL. At 100 mcg per dose, that's 10 units on a U-100 insulin syringe. A 5 mg vial with 2 mL BAC water gives 2,500 mcg/mL, so 100 mcg equals 4 units. The biggest beginner mistake is expecting results at 2x/week. Gonadorelin's subcutaneous half-life tops out around 40 minutes. Two injections per week leaves 3+ days of zero receptor stimulation between doses. If testicular preservation is the goal, nightly dosing at bedtime is the minimum frequency most experienced users and clinicians recommend. Reconstituted vials last about 14 days refrigerated at 2 to 8 degrees Celsius. At 100 mcg/night from a 2 mg vial, you'll use 700 mcg per week, which means the full 2,000 mcg lasts roughly 20 days (2.86 weeks). That exceeds the 14-day reconstituted stability window, so roughly 30% of the vial may need to be discarded. Consider using a smaller vial or splitting reconstitution across two vials to avoid waste. Use a 29 to 31 gauge, 1/2 inch insulin syringe. You'll barely feel the injection.
Dosing based on Factrel (gonadorelin HCl) FDA Prescribing Information — 7 published references.View all sources →
Cross-check your Gonadorelin reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Gonadorelin is the synthetic form of GnRH, FDA-approved since 1978. Used alongside TRT to preserve testicular function and fertility. Dosing frequency matters more than dose size; its 2 to 40 minute half-life makes protocol design the key deciding factor.