Gonadorelin Dosage Calculator
Gonadorelin is a synthetic version of gonadotropin-releasing hormone (GnRH), the 10-amino-acid peptide your hypothalamus naturally pulses every 60-120 minutes to drive testosterone and fertility.
100mcg · 2x/week
Summary: Add 2mL BAC water to your 2mg vial. Draw to 10.0 units on a U-100 syringe for a 100mcg dose. This vial will last 20 doses.
Cycle Planner
Gonadorelin Pharmacokinetics
Pharmacokinetics — Active Dose Over Time
t½ = 2-4 min (IV), ~10-40 min (SC)Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Gonadorelin Dosing Protocol
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 100mcg | 2x/week |
| Moderate | 200mcg | 2x/week |
| Aggressive | 200mcg | 3x/week |
Note: Synthetic GnRH. FDA-approved as Factrel for pituitary diagnostic testing. Pulsatile dosing is critical — continuous exposure desensitizes GnRH receptors and suppresses LH/FSH. Space injections at least 2 days apart.
About Gonadorelin
Gonadorelin is a synthetic version of gonadotropin-releasing hormone (GnRH), the 10-amino-acid peptide your hypothalamus naturally pulses every 60-120 minutes to drive testosterone and fertility. It was FDA-approved in 1978 under the brand name Factrel for diagnostic testing of pituitary gonadotroph function. Today it's widely used off-label alongside TRT to preserve testicular function and fertility, and in post-cycle therapy to restart the HPG axis after anabolic steroid use. Its extremely short half-life means dosing protocol matters more than dose size — pulsatile subcutaneous injections maintain receptor sensitivity, while continuous exposure shuts the system down.