Peptide Schedule
Gonadorelin10 residuesQHWSYGLRPGEach bubble = one amino acid. Size = residue mass. Color = chemical class.

Gonadorelin Dosage Calculator

Sexual HealthInjectionFDA Approved2-4 min half-life

Gonadorelin is a synthetic version of gonadotropin-releasing hormone (GnRH), the 10-amino-acid peptide your hypothalamus naturally pulses every 60-120 minutes to drive testosterone and fertility.

Stimulates natural LH and FSH release from the pituitaryPreserves testicular size and fertility during TRTRestarts endogenous testosterone production in PCTFDA-approved diagnostic tool with decades of clinical safety data8 weeks on / 4 weeks off

100mcg · 2x/week

100500
10.0 units
100 units (1mL)
Concentration
1,000
mcg/mL
Draw Volume
0.100
mL
Syringe Units
10.0
units
Doses / Vial
20
doses

Summary: Add 2mL BAC water to your 2mg vial. Draw to 10.0 units on a U-100 syringe for a 100mcg dose. This vial will last 20 doses.

Cycle Planner

Subcutaneous. Typical beginner frequency: 2x/week.

Gonadorelin Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = 2-4 min (IV), ~10-40 min (SC)
50%25%12.5%100%75%50%25%0%03m6m9m12m15mTime after injectionDose remaining
After 1 half-life (3m): 50% remainsAfter 2 half-lives (6m): 25% remainsAfter 3 half-lives (9m): 12.5% remains
At a 200mcg dose: 50% = 100mcg remaining after 3m. Recommended frequency: 2x/week.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

Gonadorelin Dosing Protocol

LevelDose / InjectionFrequency
Beginner100mcg2x/week
Moderate200mcg2x/week
Aggressive200mcg3x/week

Note: Synthetic GnRH. FDA-approved as Factrel for pituitary diagnostic testing. Pulsatile dosing is critical — continuous exposure desensitizes GnRH receptors and suppresses LH/FSH. Space injections at least 2 days apart.

About Gonadorelin

Gonadorelin is a synthetic version of gonadotropin-releasing hormone (GnRH), the 10-amino-acid peptide your hypothalamus naturally pulses every 60-120 minutes to drive testosterone and fertility. It was FDA-approved in 1978 under the brand name Factrel for diagnostic testing of pituitary gonadotroph function. Today it's widely used off-label alongside TRT to preserve testicular function and fertility, and in post-cycle therapy to restart the HPG axis after anabolic steroid use. Its extremely short half-life means dosing protocol matters more than dose size — pulsatile subcutaneous injections maintain receptor sensitivity, while continuous exposure shuts the system down.

Frequently Asked Questions