Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20265 Citations
Dihexa (PNB-0408) activates the HGF/c-Met pathway to promote synaptogenesis in animal models. No human trials exist. Two founding papers were retracted in 2025 for data fabrication. Community dosing runs 5 to 20 mg daily oral. Strictly experimental and unverified.
5mcg · Daily
Summary: Add 2mL BAC water to your 10mg vial. Draw to 0.1 units on a U-100 syringe for a 5mcg dose. This vial will last 2000 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 5mg | Daily |
| Moderate | 10mg | Daily |
| Aggressive | 20mg | Daily |
Dihexa is dosed in milligrams, not micrograms. That trips people up. A 5 mg dose is 5,000 mcg, which is 10 to 100 times higher than most peptide doses. Verify your units before reconstituting or weighing. For subcutaneous use: reconstitute a 10 mg vial with 2 mL bacteriostatic water. That gives you 5 mg/mL. A 5 mg dose is 1.0 mL, which is 100 units on a U-100 insulin syringe. A 10 mg dose uses the full vial (2.0 mL, 200 units). Let the powder dissolve without agitation. Oral is the more common route. Take on an empty stomach. If you're measuring raw powder, you'll want a milligram-accurate scale (plus or minus 0.5 mg). Capsule products from vendors with a third-party COA are easier than self-weighing. The 12.7-day half-life means this compound stacks in your system. By week 4, plasma levels reflect 4 to 5 half-lives of accumulation. Start low, give it time. Independent testing found 9 of 12 commercial samples below 95% purity. Demand a batch-specific HPLC plus mass spec COA from an independent third-party lab, not the vendor's own.
Dosing based on Preclinical data only: no human dosing data established — 8 published references.View all sources →
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Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Dihexa (PNB-0408) activates the HGF/c-Met pathway to promote synaptogenesis in animal models. No human trials exist. Two founding papers were retracted in 2025 for data fabrication. Community dosing runs 5 to 20 mg daily oral. Strictly experimental and unverified.