How many units of Dihexa should I draw?

It depends on your vial size, BAC water, and dose. For a 10mg vial with 2mL BAC water, a beginner dose of 5mg is typically 0 units on a U-100 syringe. Use the calculator above for your exact numbers.

How much BAC water should I add to Dihexa?

The standard amount is 2mL of bacteriostatic water for a 10mg vial. More water gives a more dilute solution — easier to measure small doses. Less water means fewer injections per vial. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

How long does a Dihexa vial last?

At a beginner dose of 5mg daily, a 10mg vial lasts about 2000 doses. The calculator shows exact doses per vial for your selected tier.

What syringe should I use for Dihexa?

Most people use a U-100 insulin syringe (1mL / 100 units). For very small doses, a U-50 or U-30 syringe gives better precision. The calculator adjusts units automatically for whichever syringe you pick.

Dihexa Dosage Calculator

CognitiveInjection/OralResearch~12.7 days half-life

Dihexa (N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, also called PNB-0408) is a small peptidomimetic derived from angiotensin IV.

Promotes synaptogenesis and dendritic spine formation in animal modelsReversed cognitive deficits in scopolamine-treated and aged ratsOrally active and blood-brain barrier permeableExtremely metabolically stable compared to native angiotensin IV6 weeks on / 6 weeks off

Vial Size

BAC Water (mL)

Dosing Level

5mcg · Daily

Custom Dose (mcg) — optional

Syringe Type

0.1 units

100 units (1mL)

Concentration

5,000

mcg/mL

Draw Volume

0.001

Syringe Units

0.1

units

Doses / Vial

2000

doses

Very small draw (0.1 units) — difficult to measure accurately. Consider using less BAC water for a more concentrated solution.

Try 0.5mL BAC water for an easier-to-measure draw.

Summary: Add 2mL BAC water to your 10mg vial. Draw to 0.1 units on a U-100 syringe for a 5mcg dose. This vial will last 2000 doses.

Cycle Planner

Cycle Length (weeks)

Price Per Vial ($) — optional

Oral or Subcutaneous. Typical beginner frequency: daily.

Dihexa Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~12.7 days (IV, rat)

After 1 half-life (13d): 50% remainsAfter 2 half-lives (25d): 25% remainsAfter 3 half-lives (38d): 12.5% remains

At a 10mcg dose: 50% = 5mcg remaining after 13d. Recommended frequency: Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

Dihexa Dosing Protocol

Level	Dose / Injection	Frequency
Beginner	5mg	Daily
Moderate	10mg	Daily
Aggressive	20mg	Daily

Note: Angiotensin IV analog. HGF/c-Met activator. Also known as PNB-0408. Preclinical only — no human trials exist. Oral or subcutaneous. Doses in mg range, not mcg like most peptides. Cycle 6 weeks on, 6 weeks off.

About Dihexa

Dihexa (N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, also called PNB-0408) is a small peptidomimetic derived from angiotensin IV. It was developed at Washington State University as a metabolically stable analog designed to cross the blood-brain barrier and activate the hepatocyte growth factor (HGF)/c-Met signaling pathway. In animal models, Dihexa has been shown to promote synaptogenesis — the formation of new functional connections between neurons — at picomolar concentrations. Rat studies demonstrated reversal of scopolamine-induced cognitive deficits and improved spatial memory in aged animals. All existing evidence comes from preclinical animal research. No human clinical trials have been conducted, and the long-term safety profile is unknown. Because Dihexa activates the HGF/c-Met proto-oncogenic pathway, there is a theoretical concern about tumor promotion with sustained use. This compound should be considered strictly experimental.

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