How many units of ARA-290 should I draw?

It depends on your vial size, BAC water, and dose. For a 5mg vial with 2mL BAC water, a beginner dose of 1000mcg is typically 40 units on a U-100 syringe. Use the calculator above for your exact numbers.

How much BAC water should I add to ARA-290?

The standard amount is 2mL of bacteriostatic water for a 5mg vial. More water gives a more dilute solution — easier to measure small doses. Less water means fewer injections per vial. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

How long does a ARA-290 vial last?

At a beginner dose of 1000mcg daily, a 5mg vial lasts about 5 doses. The calculator shows exact doses per vial for your selected tier.

What syringe should I use for ARA-290?

Most people use a U-100 insulin syringe (1mL / 100 units). For very small doses, a U-50 or U-30 syringe gives better precision. The calculator adjusts units automatically for whichever syringe you pick.

ARA-290 Dosage Calculator

Healing & RecoveryInjectionPhase 2~20 minutes half-life

ARA-290 (cibinetide) is a synthetic 11-amino-acid peptide derived from the three-dimensional structure of erythropoietin (EPO).

Promotes small nerve fiber regeneration in neuropathic conditionsReduces neuropathic pain intensity in sarcoidosis and diabetic neuropathyAnti-inflammatory action without immunosuppressionTissue-protective signaling via the innate repair receptor4 weeks on / 2 weeks off

Vial Size

BAC Water (mL)

Dosing Level

1mg · Daily

Custom Dose (mcg) — optional

Syringe Type

40.0 units

100 units (1mL)

Concentration

2,500

mcg/mL

Draw Volume

0.400

Syringe Units

40.0

units

Doses / Vial

doses

Summary: Add 2mL BAC water to your 5mg vial. Draw to 40.0 units on a U-100 syringe for a 1mg dose. This vial will last 5 doses.

Cycle Planner

Cycle Length (weeks)

Price Per Vial ($) — optional

Subcutaneous. Typical beginner frequency: daily.

ARA-290 Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~20 minutes (plasma)

After 1 half-life (20m): 50% remainsAfter 2 half-lives (40m): 25% remainsAfter 3 half-lives (1h): 12.5% remains

At a 2mg dose: 50% = 1.0mg remaining after 20m. Recommended frequency: Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

ARA-290 Dosing Protocol

Level	Dose / Injection	Frequency
Beginner	1mg	Daily
Moderate	2mg	Daily
Aggressive	4mg	Daily

Note: ARA-290 (cibinetide) is an 11-amino-acid peptide engineered from the helix B surface of erythropoietin. It selectively activates the innate repair receptor (IRR) without stimulating red blood cell production. Dose on clinical trial data: 1-4 mg SC daily for 28 days.

About ARA-290

ARA-290 (cibinetide) is a synthetic 11-amino-acid peptide derived from the three-dimensional structure of erythropoietin (EPO). It selectively activates the innate repair receptor (IRR), a heterodimer of the EPO receptor and CD131 (beta common receptor), triggering anti-inflammatory, neuroprotective, and tissue-repair signaling cascades. Unlike EPO, ARA-290 does not stimulate erythropoiesis (red blood cell production), eliminating risks of polycythemia and thrombosis. Phase 2 clinical trials have demonstrated nerve fiber regeneration and pain reduction in sarcoidosis-associated small fiber neuropathy, as well as improved metabolic control and neuropathic symptoms in type 2 diabetes.

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