Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20267 Citations
AICAR (Acadesine)Small moleculeNo amino acid sequence. Icon reflects category theme only.AICAR activates AMPK, the same metabolic sensor that fires during exercise. Banned by WADA since 2009 after mouse studies showed 44% endurance gains. Community doses are roughly 500x below animal study levels, so real-world effects remain subtle and debated among a small user base.
10mcg · Daily
Summary: Add 2mL BAC water to your 50mg vial. Draw to < 0.1 units on a U-100 syringe for a 10mcg dose. This vial will last 5000 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 10mg | Daily |
| Moderate | 25mg | Daily |
| Aggressive | 50mg | EOD |
AICAR comes as a lyophilized powder, typically in 50 mg vials. Add 2 mL of bacteriostatic water and you get 25 mg/mL concentration. Reconstitution math: at 25 mg/mL, a 10 mg dose is 0.4 mL (40 units on an insulin syringe). A 25 mg dose is 1.0 mL (100 units, a full syringe). The 50 mg aggressive dose uses the entire 2 mL vial per shot; split across two sites or grab a larger syringe. Morning dosing, fasted, aligns with natural metabolic rhythms and the fasted state amplifies AMPK signaling. On training days, inject 30 to 60 minutes before cardio. Cost adds up fast and that's the thing most beginners miss. A 14-day beginner cycle at 10 mg/day runs through about 3 vials ($150 to $195). The intermediate 25 mg/day protocol burns 7 vials ($350 to $455). Budget before you buy. Hydration matters here more than with most compounds. Your kidneys are doing the clearing. Three liters of water daily is the community standard during active cycles. AICAR is not a peptide; it's a small molecule nucleoside analog. It degrades with moisture faster than typical peptides, so keep lyophilized powder dry.
Dosing based on Dose extrapolated from animal exercise physiology studies; no approved human dosing — 13 published references.View all sources →
Cross-check your AICAR (Acadesine) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
AICAR activates AMPK, the same metabolic sensor that fires during exercise. Banned by WADA since 2009 after mouse studies showed 44% endurance gains. Community doses are roughly 500x below animal study levels, so real-world effects remain subtle and debated among a small user base.
