Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20267 Citations
Dulaglutide (Trulicity)30 residuesHGEGTFTSDVSSYLEGQAAKEFIAWLVKGREach bubble = one amino acid. Size = residue mass. Color = chemical class.Dulaglutide (Trulicity) is a once-weekly GLP-1 receptor agonist with FDA approval for type 2 diabetes and cardiovascular risk reduction. The REWIND trial confirmed a 12% drop in major cardiovascular events over 5.4 years in 9,901 participants. Pre-filled pen, no mixing, no needle. Weight loss is modest compared to newer options.
0.75mcg · Weekly
Summary: Add 0mL BAC water to your 0.75mg vial. Draw to < 0.1 units on a U-100 syringe for a 0.75mcg dose. This vial will last 0 doses.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 0.75mg | Weekly |
| Moderate | 1.5mg | Weekly |
| Aggressive | 4.5mg | Weekly |
Trulicity ships ready to inject. No vials, no bacteriostatic water, no syringe math. Each pen contains a single fixed dose with an integrated needle. Store pens in the fridge at 2 to 8 degrees Celsius. If you need to travel, they're stable at room temperature (up to 30 degrees Celsius) for 14 days. Don't freeze them. Before injection, let a cold pen sit out for about 30 minutes. Cold pens are the number one cause of activation failures and injection site stinging. Look through the pen window to confirm the solution is clear and colorless. Cloudy or discolored liquid means toss it. Four dose strengths exist: 0.75 mg, 1.5 mg, 3.0 mg, and 4.5 mg. Each pen is a single strength with no volume to measure or calculate. Start at 0.75 mg weekly. If blood sugar targets aren't met after four weeks, step up to 1.5 mg. Most community users stay at 1.5 mg long-term; that's the sweet spot between efficacy and GI tolerability for the majority. Don't rush dose escalation. GI side effects spike with every step up, and giving your gut 4 weeks to adapt makes the difference between tolerating the drug and quitting it.
Dosing based on Trulicity (dulaglutide) FDA Prescribing Information (2022) — 12 published references.View all sources →
Cross-check your Dulaglutide (Trulicity) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Dulaglutide (Trulicity) is a once-weekly GLP-1 receptor agonist with FDA approval for type 2 diabetes and cardiovascular risk reduction. The REWIND trial confirmed a 12% drop in major cardiovascular events over 5.4 years in 9,901 participants. Pre-filled pen, no mixing, no needle. Weight loss is modest compared to newer options.
