Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20269 Citations
Beta-Endorphin31 residuesYGGFMTSEKSQTPLVTLFKNAIIKNAYKKGEEach bubble = one amino acid. Size = residue mass. Color = chemical class.Beta-endorphin is the body's most powerful endogenous analgesic, 18 to 33 times stronger than morphine at the mu-opioid receptor. Studied clinically via IV and intrathecal routes in the 1980s, it remains research-only today. No subcutaneous protocol has been validated in humans.
100mcg · EOD
Summary: Add 2mL BAC water to your 1mg vial. Draw to 20.0 units on a U-100 syringe for a 100mcg dose. This vial will last 10 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 100mcg | EOD |
| Moderate | 250mcg | EOD |
| Aggressive | 500mcg | Daily |
No subcutaneous dosing protocol has ever been tested in humans. The 100 to 500 mcg SC doses listed are speculative extrapolations with zero clinical basis. Every human study used IV (2.5 to 10 mg) or intrathecal (3 mg) routes, and SC at microgram-range doses sits 10 to 100x below those studied amounts. Reconstitution math for reference: a 1 mg vial with 2 mL bacteriostatic water gives you 500 mcg/mL, so 250 mcg equals 0.5 mL (50 units on an insulin syringe). At research-reagent pricing of $155 to $203 per milligram, that single vial costs roughly $155 to $203, and a 500 mcg dose runs about $78 to $102. SC injection won't cross the blood-brain barrier. You'll get peripheral hormonal changes (LH drops, prolactin goes up, cortisol shifts) but no CNS analgesia or mood effects. If the goal is boosting the endogenous endorphin system, low-dose naltrexone (1.5 to 4.5 mg nightly) works in the opposite direction and has actual clinical evidence behind it.
Dosing based on Research use only; no established injectable dosing protocol in humans — 14 published references.View all sources →
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Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Beta-endorphin is the body's most powerful endogenous analgesic, 18 to 33 times stronger than morphine at the mu-opioid receptor. Studied clinically via IV and intrathecal routes in the 1980s, it remains research-only today. No subcutaneous protocol has been validated in humans.
