How many units of VIP (Vasoactive Intestinal Peptide) should I draw?

It depends on your vial size, BAC water, and dose. For a 5mg vial with 2mL BAC water, a beginner dose of 200mcg is typically 8 units on a U-100 syringe. Use the calculator above for your exact numbers.

How much BAC water should I add to VIP (Vasoactive Intestinal Peptide)?

The standard amount is 2mL of bacteriostatic water for a 5mg vial. More water gives a more dilute solution — easier to measure small doses. Less water means fewer injections per vial. Adjust the BAC water slider in the calculator to see how it changes your syringe units.

How long does a VIP (Vasoactive Intestinal Peptide) vial last?

At a beginner dose of 200mcg daily, a 5mg vial lasts about 25 doses. The calculator shows exact doses per vial for your selected tier.

What syringe should I use for VIP (Vasoactive Intestinal Peptide)?

Most people use a U-100 insulin syringe (1mL / 100 units). For very small doses, a U-50 or U-30 syringe gives better precision. The calculator adjusts units automatically for whichever syringe you pick.

VIP (Vasoactive Intestinal Peptide) Dosage Calculator

ImmuneNasalResearch~1-2 minutes half-life

VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide produced throughout the body, with high concentrations in the gut, lungs, and brain.

Reduces chronic inflammation by suppressing NF-kB and pro-inflammatory cytokinesNormalizes TGF-beta 1, C4a, VEGF, and MMP-9 levels in CIRS patientsRestores regulatory T-cell function and rebalances immune responseIncreases grey matter nuclear volume in the brain (demonstrated on NeuroQuant MRI)12 weeks on / 4 weeks off

Vial Size

BAC Water (mL)

Dosing Level

200mcg · Daily

Custom Dose (mcg) — optional

Syringe Type

8.0 units

100 units (1mL)

Concentration

2,500

mcg/mL

Draw Volume

0.080

Syringe Units

8.0

units

Doses / Vial

doses

Summary: Add 2mL BAC water to your 5mg vial. Draw to 8.0 units on a U-100 syringe for a 200mcg dose. This vial will last 25 doses.

Cycle Planner

Cycle Length (weeks)

Price Per Vial ($) — optional

Intranasal. Typical beginner frequency: daily.

VIP (Vasoactive Intestinal Peptide) Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~1-2 minutes (plasma)

After 1 half-life (2m): 50% remainsAfter 2 half-lives (3m): 25% remainsAfter 3 half-lives (5m): 12.5% remains

At a 200mcg dose: 50% = 100mcg remaining after 2m. Recommended frequency: 2x Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

VIP (Vasoactive Intestinal Peptide) Dosing Protocol

Level	Dose / Injection	Frequency
Beginner	200mcg	Daily
Moderate	200mcg	2x Daily
Aggressive	400mcg	2x Daily

Note: Intranasal administration only. Used as the final step (step 11) in the Shoemaker CIRS protocol. Must address prior steps (cholestyramine, MARCoNS eradication, etc.) before starting VIP. Each dose is 4 sprays at 50 mcg per spray (200 mcg total per dose). Do not start VIP if VCS test is still failing or MARCoNS is still present.

About VIP (Vasoactive Intestinal Peptide)

VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide produced throughout the body, with high concentrations in the gut, lungs, and brain. It acts as both a neurotransmitter and an immune modulator. In the context of CIRS (Chronic Inflammatory Response Syndrome) caused by mold and biotoxin exposure, VIP is used intranasally to reduce persistent inflammation, normalize dysregulated cytokines like TGF-beta and MMP-9, restore regulatory T-cell function, and improve grey matter volume in the brain. It is the final therapeutic step in Dr. Ritchie Shoemaker's published CIRS treatment protocol, used only after all preceding interventions have been completed.

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