Thymulin (FTS) Dosage Calculator
Thymulin, originally known as Facteur Thymique Serique (FTS) or Serum Thymic Factor, is a metallopeptide hormone produced exclusively by thymic epithelial cells.
50mcg · 2x/week
Summary: Add 2mL BAC water to your 1mg vial. Draw to 10.0 units on a U-100 syringe for a 50mcg dose. This vial will last 20 doses.
Cycle Planner
Thymulin (FTS) Pharmacokinetics
Pharmacokinetics — Active Dose Over Time
t½ = ~10 minutes (serum half-life)Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Thymulin (FTS) Dosing Protocol
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 50mcg | 2x/week |
| Moderate | 100mcg | 3x/week |
| Aggressive | 200mcg | Daily |
Note: Zinc-dependent nonapeptide thymic hormone. Requires equimolar zinc binding for biological activity. Co-administer with 15-30 mg/day elemental zinc. Extremely short plasma half-life means frequent dosing or sustained-release strategies may be needed. Distinct from Thymalin — Thymulin is a single defined 9-amino-acid peptide (pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn), while Thymalin is a polypeptide thymic extract.
About Thymulin (FTS)
Thymulin, originally known as Facteur Thymique Serique (FTS) or Serum Thymic Factor, is a metallopeptide hormone produced exclusively by thymic epithelial cells. It is a nonapeptide (pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn) with a molecular weight of 858.9 Da that requires equimolar zinc binding to adopt its biologically active conformation. The zinc ion coordinates through the side chains of Lys3 and Ser4 and the backbone carbonyl of Ala2, creating a specific three-dimensional structure confirmed by NMR studies. Without zinc, the peptide is inactive. This zinc dependency means that thymulin serves as a direct molecular link between zinc nutritional status and immune function. Thymulin acts primarily on T-cell populations, promoting the differentiation and maturation of immature T-cell precursors in the thymus and periphery. It binds to high-affinity receptors on T cells and enhances allogenic cytotoxicity, suppressor cell function, and interleukin-2 (IL-2) production. Beyond T-cell effects, it modulates natural killer cell activity, influences dendritic cell function, and has emerged as a significant anti-inflammatory molecule. Circulating thymulin levels peak during early childhood and decline progressively with age, mirroring thymic involution. By age 60, serum levels are often undetectable. This age-related decline has made thymulin a target of interest in immunosenescence research, with gene therapy approaches being explored to restore sustained production.