Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20265 Citations
Romiplostim (Nplate)14 residuesIEGPTLRQWLAARAEach bubble = one amino acid. Size = residue mass. Color = chemical class.Romiplostim (Nplate) is an FDA-approved peptibody for immune thrombocytopenia. The Lancet 2008 RCT confirmed a 79% platelet response rate. Weekly subcutaneous dosing at 1 to 10 mcg/kg. Long-term registry data spans five years of active use without new safety signals emerging.
1mcg · Weekly
Summary: Add 0.72mL BAC water to your 0.25mg vial. Draw to 0.3 units on a U-100 syringe for a 1mcg dose. This vial will last 250 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 1mcg | Weekly |
| Moderate | 3mcg | Weekly |
| Aggressive | 10mcg | Weekly |
Romiplostim is weight-based dosing, so the math changes for every patient. Start at 1 mcg/kg weekly. For a 70 kg person, that's 70 mcg. Reconstitution: add 0.72 mL of sterile water for injection to a 250 mcg vial. That gives you 500 mcg/mL. Swirl gently; don't shake it. Let the vial sit about five minutes until the solution is clear and colorless. Syringe math for a 70 kg patient on a U-100 insulin syringe at 500 mcg/mL: 70 mcg equals 0.14 mL, which is 14 units. At 3 mcg/kg (210 mcg), you'd pull 42 units. At the max dose of 10 mcg/kg (700 mcg), that's 140 units, so you'd need a 500 mcg vial reconstituted with 1.2 mL sterile water (also yielding 500 mcg/mL). Don't pool unused portions from multiple vials. The FDA label explicitly prohibits it. Single-use only; discard what's left. Store reconstituted solution at room temperature or refrigerated, but use it within 24 hours.
Dosing based on Nplate (romiplostim) FDA Prescribing Information (2021) — 7 published references.View all sources →
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Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Romiplostim (Nplate) is an FDA-approved peptibody for immune thrombocytopenia. The Lancet 2008 RCT confirmed a 79% platelet response rate. Weekly subcutaneous dosing at 1 to 10 mcg/kg. Long-term registry data spans five years of active use without new safety signals emerging.
