Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20266 Citations
Pramlintide (Symlin)37 residuesKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYEach bubble = one amino acid. Size = residue mass. Color = chemical class.Beginner, moderate, and aggressive dosing amounts with timing. Free, no signup.
Subcutaneous
Pramlintide (Symlin) has no standard bacteriostatic water volume on file, so there are no syringe units to calculate here. Dosing runs 15mcg to 120mcg per administration, before each major meal (>=250 kcal or >=30 g carb). A 1mg supply covers about 66 doses at the beginner tier.
If your product does arrive as a powder, use the universal reconstitution calculator and enter your own vial size and water volume.
Pramlintide (Symlin) is the only FDA-approved amylin analog, replacing a hormone absent in T1D and impaired in T2D. Flattens postprandial glucose 3.4 to 5 mmol/L beyond insulin alone. Carries a black box warning for hypoglycemia. Commercially discontinued in October 2025.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 15mcg | Before each major meal (>=250 kcal or >=30 g carb) |
| Moderate | 60mcg | Before each major meal (>=250 kcal or >=30 g carb) |
| Aggressive | 120mcg | Before each major meal (>=250 kcal or >=30 g carb) |
Symlin ships as a pre-filled solution at 1000 mcg/mL. No lyophilized powder, no reconstitution, no bacteriostatic water. The math for syringe units is straightforward on a U-100 insulin syringe: 15 mcg equals 1.5 units, 30 mcg equals 3 units, 60 mcg equals 6 units, 120 mcg equals 12 units. If you're drawing from a vial rather than a pen (remaining stock varies), confirm the concentration is 1000 mcg/mL before calculating. A wrong concentration assumption creates a proportional dosing error. The thing most people miss: T1D and T2D dose ceilings are different. Type 1 diabetes max is 60 mcg per meal. Type 2 diabetes max is 120 mcg per meal. A T1D patient taking 120 mcg is taking double their approved maximum. Always confirm diabetes type before dosing above 60 mcg. Inject within 15 minutes before a major meal containing at least 250 kcal and 30g of carbohydrates. Skipping a meal after injecting is how hypoglycemia happens when there is no incoming glucose to offset the drug's effects. If you forget a dose, skip it entirely and resume at the next major meal. Never double up.
Dosing based on Symlin (pramlintide acetate) FDA Prescribing Information (2014) — 10 published references.View all sources →
Cross-check your Pramlintide (Symlin) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
