Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20266 Citations
Pramlintide (Symlin)37 residuesKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYEach bubble = one amino acid. Size = residue mass. Color = chemical class.Pramlintide (Symlin) is the only FDA-approved amylin analog, replacing a hormone absent in T1D and impaired in T2D. Flattens postprandial glucose 3.4 to 5 mmol/L beyond insulin alone. Carries a black box warning for hypoglycemia. Commercially discontinued in October 2025.
15mcg · 3x Daily (before major meals)
Summary: Add 0mL BAC water to your 1mg vial. Draw to < 0.1 units on a U-100 syringe for a 15mcg dose. This vial will last 0 doses.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 15mcg | 3x Daily (before major meals) |
| Moderate | 60mcg | 3x Daily (before major meals) |
| Aggressive | 120mcg | 3x Daily (before major meals) |
Symlin ships as a pre-filled solution at 1000 mcg/mL. No lyophilized powder, no reconstitution, no bacteriostatic water. The math for syringe units is straightforward on a U-100 insulin syringe: 15 mcg equals 1.5 units, 30 mcg equals 3 units, 60 mcg equals 6 units, 120 mcg equals 12 units. If you're drawing from a vial rather than a pen (remaining stock varies), confirm the concentration is 1000 mcg/mL before calculating. A wrong concentration assumption creates a proportional dosing error. The thing most people miss: T1D and T2D dose ceilings are different. Type 1 diabetes max is 60 mcg per meal. Type 2 diabetes max is 120 mcg per meal. A T1D patient taking 120 mcg is taking double their approved maximum. Always confirm diabetes type before dosing above 60 mcg. Inject within 15 minutes before a major meal containing at least 250 kcal and 30g of carbohydrates. Skipping a meal after injecting is how hypoglycemia happens when there is no incoming glucose to offset the drug's effects. If you forget a dose, skip it entirely and resume at the next major meal. Never double up.
Dosing based on Symlin (pramlintide acetate) FDA Prescribing Information (2014) — 10 published references.View all sources →
Cross-check your Pramlintide (Symlin) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Pramlintide (Symlin) is the only FDA-approved amylin analog, replacing a hormone absent in T1D and impaired in T2D. Flattens postprandial glucose 3.4 to 5 mmol/L beyond insulin alone. Carries a black box warning for hypoglycemia. Commercially discontinued in October 2025.
