Peptide Schedule
NA-Selank Amidate7 residuesTKPRPGPEach bubble = one amino acid. Size = residue mass. Color = chemical class.

NA-Selank Amidate Dosage Calculator

CognitiveNasalResearch~2-3 min half-life

NA-Selank Amidate is a stabilized derivative of Selank, itself a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg).

Anxiolytic effects comparable to low-dose benzodiazepines without sedation, tolerance, or dependenceUpregulates BDNF expression in the hippocampus for enhanced neuroplasticity and memoryInhibits enkephalin-degrading enzymes, raising endogenous opioid peptide levelsReduces pro-inflammatory cytokines (IL-6, IL-1-beta, TNF-alpha) under stress conditions4 weeks on / 2 weeks off

200mcg · 2x Daily

100500
0.0 units
100 units (1mL)
Concentration
0
mcg/mL
Draw Volume
< 0.001
mL
Syringe Units
< 0.1
units
Doses / Vial
0
doses

Summary: Add 0mL BAC water to your 5mg vial. Draw to < 0.1 units on a U-100 syringe for a 200mcg dose. This vial will last 0 doses.

Cycle Planner

Intranasal. Typical beginner frequency: 2x daily.

NA-Selank Amidate Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~2-3 min (plasma); functional effects persist 6-8 hours via downstream gene expression
50%25%12.5%100%75%50%25%0%07h14h21h28h35hTime after injectionDose remaining
After 1 half-life (7h): 50% remainsAfter 2 half-lives (14h): 25% remainsAfter 3 half-lives (21h): 12.5% remains
At a 400mcg dose: 50% = 200mcg remaining after 7h. Recommended frequency: 2x Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

NA-Selank Amidate Dosing Protocol

LevelDose / InjectionFrequency
Beginner200mcg2x Daily
Moderate400mcg2x Daily
Aggressive600mcg3x Daily

Note: N-acetylated, C-amidated analog of Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro). The acetyl and amide modifications improve enzymatic stability and nasal membrane permeability compared to native Selank. Administered intranasally as a pre-mixed nasal spray — no reconstitution needed. Approved in Russia as an anxiolytic for GAD and neurasthenia under the parent Selank formulation.

About NA-Selank Amidate

NA-Selank Amidate is a stabilized derivative of Selank, itself a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg). The N-terminal acetylation and C-terminal amidation modifications protect the peptide from rapid degradation by aminopeptidases and carboxypeptidases, extending its functional half-life after intranasal delivery. NA-Selank Amidate acts through multiple converging mechanisms: positive allosteric modulation of GABA-A receptors (producing anxiolytic effects comparable to low-dose benzodiazepines without sedation or dependence), inhibition of enkephalin-degrading enzymes (raising endogenous enkephalin levels), upregulation of BDNF expression in the hippocampus, and modulation of pro-inflammatory cytokines including IL-6, IL-1-beta, and TNF-alpha. Clinical trials of the parent compound Selank in patients with generalized anxiety disorder demonstrated efficacy comparable to medazepam, with additional antiasthenic and mild nootropic properties not seen with benzodiazepine comparators.

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