Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20269 Citations
Matrixyl 30007 residues (approx.)GHKGQPREach bubble = one amino acid. Size = residue mass. Color = chemical class.Uses closest standard amino acids for non-standard residues.Beginner, moderate, and aggressive dosing amounts with timing. Free, no signup.
Topical
Matrixyl 3000 has no standard bacteriostatic water volume on file, so there are no syringe units to calculate here. Dosing runs 2mg to 10mg per administration, daily. A 5mg supply covers about 2 doses at the beginner tier.
If your product does arrive as a powder, use the universal reconstitution calculator and enter your own vial size and water volume.
Matrixyl 3000 pairs two matrikine peptides for dual-action anti-aging: collagen synthesis plus anti-inflammatory protection. Sederma's clinical trial showed 45% wrinkle reduction at 2 months. Topical, well-tolerated, compatible with retinoids and vitamin C. Community-favorite upgrade over original Matrixyl. Works in both AM and PM routines.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 2mg | Daily |
| Moderate | 5mg | 2x Daily |
| Aggressive | 10mg | 2x Daily |
This one is topical, so no vials, no syringes, no bacteriostatic water. You're shopping for a serum, not a lyophilized powder. The number that matters is complex concentration. Sederma's clinical data used 3% Matrixyl 3000 complex. Products that list "Matrixyl 3000" without disclosing the percentage probably contain too little to match clinical results. Look for palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 both appearing in the top 10 INCI ingredients; if they're near the bottom, the concentration is cosmetic-grade marketing rather than clinical-grade dosing. The Ordinary's Matrixyl 10% + HA lists 10% combined Matrixyl 3000 and Matrixyl Synthe'6 at about $15 for 30ml. That's transparent labeling. Paula's Choice Peptide Booster runs $58 for 20ml. Raw Sederma complex costs $80 to $200 per gram for DIY formulators. Apply to clean, dry skin. Wait 2 to 3 minutes before layering other products. If you're using GHK-Cu in the same routine, apply that first (lower molecular weight, faster absorption). Retinoid and Matrixyl 3000 work fine together but if your skin is sensitive, split them: Matrixyl AM, retinoid PM.
Dosing based on Cosmeceutical industry standard concentrations — 10 published references.View all sources →
Cross-check your Matrixyl 3000 reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
