Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20268 Citations
Leuprolide (Lupron)9 residuesHWSYGLRPGEach bubble = one amino acid. Size = residue mass. Color = chemical class.Beginner, moderate, and aggressive dosing amounts with timing. Free, no signup.
Subcutaneous or Intramuscular
Leuprolide (Lupron) has no standard bacteriostatic water volume on file, so there are no syringe units to calculate here. Dosing runs 1mg to 22.5mg per administration, daily. A 5mg supply covers about 5 doses at the beginner tier.
If your product does arrive as a powder, use the universal reconstitution calculator and enter your own vial size and water volume.
Leuprolide (Lupron) is an FDA-approved GnRH agonist prescribed for prostate cancer, endometriosis, uterine fibroids, and precocious puberty. Depot formulations cover monthly to six-month dosing. The initial hormone flare requires careful management, and bone density monitoring is standard during therapy. Over 4,160 PubMed publications support its clinical profile.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 1mg | Daily |
| Moderate | 7.5mg | Monthly |
| Aggressive | 22.5mg | Every 3 months |
Leuprolide comes in very different formulations, and mixing them up is the most common beginner mistake. The daily subcutaneous injection is 1 mg/day from a 5 mg/mL vial (0.2 mL per dose, which is 20 units on a U-100 insulin syringe). That formulation needs refrigeration at 2 to 8 degrees C. The depot kits are a completely different product. Lupron Depot comes as lyophilized microspheres that you reconstitute with the included diluent. Swirl gently; never shake. The suspension should look uniform and milky white. Inject it immediately after mixing. You can't store reconstituted depot. Depot kits store at room temperature (15 to 30 degrees C). Don't refrigerate them. For prostate cancer patients: the bicalutamide pre-load before your first injection isn't optional if you have bone mets or high tumor burden. Start it seven days before the first depot shot. For endometriosis patients: norethindrone 5 mg/day add-back from day one reduces hot flashes and protects bone density. Most community members and current guidelines strongly recommend it.
Dosing based on Lupron Depot (leuprolide acetate) FDA Prescribing Information (2012) — 12 published references.View all sources →
Cross-check your Leuprolide (Lupron) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
