Peptide Schedule
Lactoferricin B (LfcinB)25 residues (approx.)FKCRRWQWRMKKLGAPSITCVRRAFEach bubble = one amino acid. Size = residue mass. Color = chemical class.Uses closest standard amino acids for non-standard residues.

Lactoferricin B (LfcinB) Dosage Calculator

ImmuneInjection/TopicalResearch~2-4 hours half-life

Lactoferricin B is a 25-residue antimicrobial peptide (FKCRRWQWRMKKLGAPSITCVRRAF) derived from the N-terminal region of bovine lactoferrin through pepsin hydrolysis.

Broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria, fungi, and parasitesDirect membrane-disrupting mechanism reduces likelihood of resistance developmentSelective cytotoxicity against cancer cell lines (leukemia, neuroblastoma, fibrosarcoma) while sparing normal cellsEnhances innate immune responses via macrophage activation and increased nitric oxide production8 weeks on / 4 weeks off

50mcg · Daily

100500
5.0 units
100 units (1mL)
Concentration
1,000
mcg/mL
Draw Volume
0.050
mL
Syringe Units
5.0
units
Doses / Vial
40
doses

Summary: Add 2mL BAC water to your 2mg vial. Draw to 5.0 units on a U-100 syringe for a 50mcg dose. This vial will last 40 doses.

Cycle Planner

Subcutaneous / Topical (research settings). Typical beginner frequency: daily.

Lactoferricin B (LfcinB) Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~2-4 hours (estimated; rapid proteolytic degradation in vivo)
50%25%12.5%100%75%50%25%0%03h6h9h12h15hTime after injectionDose remaining
After 1 half-life (3h): 50% remainsAfter 2 half-lives (6h): 25% remainsAfter 3 half-lives (9h): 12.5% remains
At a 100mcg dose: 50% = 50mcg remaining after 3h. Recommended frequency: Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

Lactoferricin B (LfcinB) Dosing Protocol

LevelDose / InjectionFrequency
Beginner50mcgDaily
Moderate100mcgDaily
Aggressive200mcgDaily

Note: Lactoferricin B (LfcinB) is a 25-amino-acid cationic antimicrobial peptide (residues 17-41 of bovine lactoferrin) generated by pepsin cleavage. It contains an amphipathic beta-sheet stabilized by a single disulfide bond (Cys19-Cys36) and carries a net charge of approximately +8 at physiological pH. LfcinB demonstrates broader and more potent antimicrobial activity than its parent protein lactoferrin. It has been studied extensively for its direct membrane-disrupting mechanism against bacteria, fungi, and parasites, as well as its immunomodulatory and antitumor properties. Research use only — not approved for clinical use.

About Lactoferricin B (LfcinB)

Lactoferricin B is a 25-residue antimicrobial peptide (FKCRRWQWRMKKLGAPSITCVRRAF) derived from the N-terminal region of bovine lactoferrin through pepsin hydrolysis. First isolated and characterized in 1992 by Bellamy et al., it represents one of the most studied naturally derived antimicrobial peptides. The peptide adopts a twisted beta-sheet conformation in solution, stabilized by an intramolecular disulfide bridge. Its high cationic charge and amphipathic structure enable direct interaction with negatively charged microbial membranes, causing membrane permeabilization and cell death. Beyond antimicrobial activity, LfcinB exerts immunomodulatory effects by promoting macrophage and NK cell activation, and demonstrates selective cytotoxicity against cancer cell lines while sparing normal cells. These multifunctional properties have made it a subject of intense research in antimicrobial defense, cancer biology, and immune modulation.

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