Peptide Schedule
Ghrelin28 residuesGSSFLSPEHQRVQQRKESKKPPAKLQPREach bubble = one amino acid. Size = residue mass. Color = chemical class.

Ghrelin Dosage Calculator

MetabolicInjectionResearch~30 minutes half-life

Ghrelin is a 28-amino-acid peptide hormone discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor (GHS-R1a).

Potent stimulation of growth hormone release via the GHS-R1a receptorAppetite stimulation — useful in cachexia, anorexia, and wasting conditionsEnhanced gastric motility and gastroprokinetic effectsNeuroprotective properties observed in preclinical models8 weeks on / 4 weeks off

50mcg · Daily

100500
2.0 units
100 units (1mL)
Concentration
2,500
mcg/mL
Draw Volume
0.020
mL
Syringe Units
2.0
units
Doses / Vial
100
doses
Very small draw (2.0 units) — difficult to measure accurately. Consider using less BAC water for a more concentrated solution.
Try 1mL BAC water for an easier-to-measure draw.

Summary: Add 2mL BAC water to your 5mg vial. Draw to 2.0 units on a U-100 syringe for a 50mcg dose. This vial will last 100 doses.

Cycle Planner

Subcutaneous / Intravenous. Typical beginner frequency: daily.

Ghrelin Pharmacokinetics

Pharmacokinetics — Active Dose Over Time

t½ = ~30 minutes (IV), ~60-90 minutes (SC)
50%25%12.5%100%75%50%25%0%01h3h4h5h6hTime after injectionDose remaining
After 1 half-life (1h): 50% remainsAfter 2 half-lives (3h): 25% remainsAfter 3 half-lives (4h): 12.5% remains
At a 100mcg dose: 50% = 50mcg remaining after 1h. Recommended frequency: 2x Daily.

Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.

Ghrelin Dosing Protocol

LevelDose / InjectionFrequency
Beginner50mcgDaily
Moderate100mcg2x Daily
Aggressive200mcg2x Daily

Note: Endogenous 28-amino-acid orexigenic hormone with octanoyl modification at Ser3. Natural ligand of GHS-R1a. Primarily secreted by gastric oxyntic cells. Rapid degradation by esterases — acylated form is the bioactive species. Not widely available as a research peptide; MK-677, GHRP-2, and GHRP-6 are more commonly used synthetic GHS-R agonists.

About Ghrelin

Ghrelin is a 28-amino-acid peptide hormone discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor (GHS-R1a). Uniquely among mammalian peptides, it carries an octanoyl (C8 fatty acid) modification on its third serine residue, which is essential for receptor binding and biological activity. Produced primarily by enteroendocrine cells in the stomach fundus, ghrelin is the only known circulating orexigenic (appetite-stimulating) hormone. It plays a central role in energy homeostasis by stimulating appetite, promoting growth hormone release from the anterior pituitary, regulating gastric motility, and modulating glucose metabolism. Ghrelin levels rise before meals and fall after eating, earning it the designation as the "hunger hormone."

Frequently Asked Questions