Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20264 Citations
Eptifibatide (Integrilin)8 residuesHARGDWPCEach bubble = one amino acid. Size = residue mass. Color = chemical class.Eptifibatide (Integrilin) is an FDA-approved GP IIb/IIIa inhibitor given by IV during heart attacks and coronary stenting. Backed by the PURSUIT (n=10,948) and ESPRIT trials, it blocks platelet aggregation within minutes. Hospital use only, with platelet recovery in 4 to 8 hours.
180mcg · Single dose
Summary: Add 0mL BAC water to your 20mg vial. Draw to < 0.1 units on a U-100 syringe for a 180mcg dose. This vial will last 0 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 180 mcg/kg | Single dose |
| Moderate | 180 mcg/kg | Single dose |
| Aggressive | 180 mcg/kg | Double bolus (x2, 10 min apart) |
Eptifibatide comes ready to use. No reconstitution needed. Two vial concentrations exist: 2 mg/mL in a 10 mL bolus vial (20 mg total) and 0.75 mg/mL in a 100 mL infusion vial (75 mg total). Mixing up the two vials is a recognized medication error. For the weight-based math on a 70 kg patient: 180 mcg/kg equals 12,600 mcg (12.6 mg). From the 2 mg/mL bolus vial, that's 6.3 mL. The continuous infusion at 2 mcg/kg/min equals 140 mcg/min, which is 8.4 mg/h. From the 100 mL infusion vial (0.75 mg/mL), the rate comes to 11.2 mL/h. The mistake that trips up cath lab teams most often is flat-dosing instead of weight-based dosing. Writing "180 mcg" instead of "180 mcg/kg" underdoses by a factor of 70. Always confirm the calculation: dose equals the per-kg value times actual body weight in kilograms; use actual weight, not ideal. Store vials at 2 to 8 degrees Celsius, protected from light. Don't freeze. Use opened vials within 24 hours.
Dosing based on INTEGRILIN (eptifibatide) FDA Prescribing Information (2021) — 8 published references.View all sources →
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Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Eptifibatide (Integrilin) is an FDA-approved GP IIb/IIIa inhibitor given by IV during heart attacks and coronary stenting. Backed by the PURSUIT (n=10,948) and ESPRIT trials, it blocks platelet aggregation within minutes. Hospital use only, with platelet recovery in 4 to 8 hours.
