Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20268 Citations
Cortexin is a bovine/porcine cortex-derived neuropeptide bioregulator approved in Russia since 1999 for stroke and TBI recovery. A 189-patient multicenter RCT (PMID 29652367) confirmed neurological improvement. Effects are delayed, peaking 1 to 4 weeks after the 10-day IM course ends.
5mcg · Daily
Summary: Add 2mL BAC water to your 5mg vial. Draw to 0.2 units on a U-100 syringe for a 5mcg dose. This vial will last 1000 doses.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 5mg | Daily |
| Moderate | 10mg | Daily |
| Aggressive | 10mg | 2x Daily |
Cortexin ships as a lyophilized powder in 5 mg or 10 mg vials. You'll reconstitute each vial with 1 to 2 mL of sterile water for injection right before use. Don't store the reconstituted solution; use it immediately. For a 10 mg vial reconstituted with 1 mL sterile water: you get 10 mg/mL concentration. Draw up 100 units (the full 1.0 mL) on a U100 insulin syringe for a 10 mg dose. For the 5 mg beginner dose from a 10 mg vial, draw 50 units (0.5 mL). For a 5 mg vial with 1 mL water, the full syringe is your dose. The non-obvious thing most beginners miss: you won't feel much during the 10-day course. Peak effects show up 1 to 4 weeks after the last injection. Evaluating at Day 10 is the single most common mistake; give it a full month before judging. If the injection hurts, switch your diluent from sterile water to 0.5% procaine solution (unless you have a local anesthetic allergy). Deep IM injection into deltoid or gluteal muscle, rotated daily, minimizes site reactions. Cold-chain matters; inspect the powder on arrival. It should be white to off-white. Discard if discolored, clumped, or if the vial seal is broken.
Dosing based on Russian registered pharmaceutical: 10 mg IM daily for 10 days (stroke rehabilitation RCTs) — 12 published references.View all sources →
Cross-check your Cortexin reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Cortexin is a bovine/porcine cortex-derived neuropeptide bioregulator approved in Russia since 1999 for stroke and TBI recovery. A 189-patient multicenter RCT (PMID 29652367) confirmed neurological improvement. Effects are delayed, peaking 1 to 4 weeks after the 10-day IM course ends.