Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 202610 Citations
CGRP (Calcitonin Gene-Related Peptide)37 residuesACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFEach bubble = one amino acid. Size = residue mass. Color = chemical class.CGRP is the body's most potent vasodilator and the central target behind all modern migraine biologics. Strong preclinical evidence supports cardioprotective and wound healing roles. Exogenous use is IV-only with a 6.9-minute half-life, restricting it to controlled research settings.
10mcg · Single dose
Summary: Add 2mL BAC water to your 0.5mg vial. Draw to 4.0 units on a U-100 syringe for a 10mcg dose. This vial will last 50 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 10mcg | Single dose |
| Moderate | 30mcg | Single dose |
| Aggressive | 60mcg | Single dose |
CGRP is not a self-administration peptide. This needs to be stated plainly because the peptide shows up in search results alongside injectable peptides that people do use at home. The 6.9-minute half-life means subcutaneous injection produces a brief, unpredictable hemodynamic event with no sustained benefit. Every published human study used IV infusion with continuous blood pressure monitoring. Reconstitution math for research settings: a 0.5 mg (500 mcg) vial reconstituted with 2 mL bacteriostatic water yields 250 mcg/mL. For the standard migraine provocation dose of 1.5 mcg/min over 20 minutes (30 mcg total), you'd need 0.12 mL of that solution diluted into an IV infusion bag. A 1 mg vial with 2 mL gives 500 mcg/mL. The detail most people miss: CGRP adsorbs to glass and plastic surfaces at low concentrations. Below 10 mcg/mL, add 0.1% BSA (bovine serum albumin) as a carrier protein and use siliconized or protein low-bind containers. Skip this step and your actual delivered dose could be noticeably lower than intended.
Dosing based on Very limited human dosing data: extrapolated from migraine research; therapeutic antibodies differ in dose — 15 published references.View all sources →
Cross-check your CGRP (Calcitonin Gene-Related Peptide) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
CGRP is the body's most potent vasodilator and the central target behind all modern migraine biologics. Strong preclinical evidence supports cardioprotective and wound healing roles. Exogenous use is IV-only with a 6.9-minute half-life, restricting it to controlled research settings.
