Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20267 Citations
Cholecystokinin (CCK-8)8 residuesDYMGWMDFEach bubble = one amino acid. Size = residue mass. Color = chemical class.CCK-8 is the body's own meal-stop signal, a sulfated octapeptide that fires from the gut within minutes of eating. Its 2 to 5 minute half-life limits it to IV research settings. The FDA-approved diagnostic form (sincalide) has been in clinical use since 1976.
1mcg · Single dose
Summary: Add 2mL BAC water to your 0.5mg vial. Draw to 0.4 units on a U-100 syringe for a 1mcg dose. This vial will last 500 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 1mcg | Single dose |
| Moderate | 2mcg | Single dose |
| Aggressive | 4mcg | Single dose |
CCK-8 is not a typical research peptide. All validated human dosing is intravenous, and most people encounter it only as sincalide (Kinevac) during a gallbladder imaging study. Source from established biochemical suppliers only: Tocris (Cat# 1166), Bachem (4033010), or Cayman Chemical (23371). Do not use gray-market peptide vendors for anything going IV. You need the sulfated form (CCK-8S). The sulfated tyrosine at position 7 is required for full CCK1 receptor potency; the non-sulfated version has roughly 1000-fold lower affinity. If satiety and gallbladder effects don't materialize, wrong form is the first thing to check. Confirm on the Certificate of Analysis before ordering. Reconstitution math for a 1 mg vial: add 2 mL bacteriostatic water to get 500 mcg/mL. A 2.8 mcg dose (0.04 mcg/kg for a 70 kg adult) comes to 0.0056 mL, which is 0.56 units on a U-100 insulin syringe. These volumes are extremely small, so research protocols dilute the stock into 50 mL normal saline for controlled IV infusion. Store lyophilized powder at -20C desiccated. Reconstituted solution goes at 2 to 8C, use within 7 days. The sulfate ester hydrolyzes at room temperature.
Dosing based on Research use only; no established injectable human dosing protocol — 9 published references.View all sources →
Cross-check your Cholecystokinin (CCK-8) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
CCK-8 is the body's own meal-stop signal, a sulfated octapeptide that fires from the gut within minutes of eating. Its 2 to 5 minute half-life limits it to IV research settings. The FDA-approved diagnostic form (sincalide) has been in clinical use since 1976.
