Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20267 Citations
Beginner, moderate, and aggressive dosing amounts with timing. Free, no signup.
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
| Moderate | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
| Aggressive | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
Intravenous
Bivalirudin (Angiomax) has no standard bacteriostatic water volume on file, so there are no syringe units to calculate here. Dosing runs 750mcg/kg to 750mcg/kg per administration, iv bolus, then 1.75 mg/kg/h infusion for the procedure.
If your product does arrive as a powder, use the universal reconstitution calculator and enter your own vial size and water volume.
Bivalirudin (Angiomax) is an FDA-approved direct thrombin inhibitor used during coronary stent procedures. The HORIZONS-AMI trial showed 41% lower major bleeding versus heparin-based regimens. Its 25-minute half-life allows rapid offset, and it eliminates the risk of heparin-induced thrombocytopenia entirely. Hospital-only IV administration.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
| Moderate | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
| Aggressive | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
This is a hospital-only IV drug. You won't be reconstituting this at home; cath lab pharmacists and nurses handle preparation under physician supervision. Reconstitution math for the record: each 250 mg vial gets 5 mL of Sterile Water for Injection (SWFI), giving a 50 mg/mL concentrate. That concentrate then gets diluted into 50 mL of D5W or 0.9% NaCl for a final working concentration of 5 mg/mL. For an 80 kg patient, the bolus is 60 mg (0.75 mg/kg x 80 kg), which works out to 12 mL from the 5 mg/mL solution. The procedural infusion runs at 140 mg/h (1.75 mg/kg/h x 80 kg), so 28 mL/h from the same bag. The non-obvious thing most clinicians miss early on: a subtherapeutic ACT at the 5-minute check almost always traces back to a weight calculation error. Recheck actual body weight before giving the supplemental 0.3 mg/kg bolus. Estimated weights in emergency STEMI settings cause real dosing errors.
Dosing based on ANGIOMAX (bivalirudin) FDA Prescribing Information (2019): 7 published references.View all sources →
Cross-check your Bivalirudin (Angiomax) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.