Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20266 Citations
Beginner, moderate, and aggressive dosing amounts with timing. Free, no signup.
Intravenous
Bivalirudin (Angiomax) has no standard bacteriostatic water volume on file, so there are no syringe units to calculate here. Dosing runs 750mcg/kg to 750mcg/kg per administration, iv bolus, then 1.75 mg/kg/h infusion for the procedure.
If your product does arrive as a powder, use the universal reconstitution calculator and enter your own vial size and water volume.
Bivalirudin (Angiomax) is an FDA-approved direct thrombin inhibitor used during coronary stent procedures. The HORIZONS-AMI trial showed 41% lower major bleeding versus heparin-based regimens. Its 25-minute half-life allows rapid offset, and it eliminates the risk of heparin-induced thrombocytopenia entirely. Hospital-only IV administration.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
| Moderate | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
| Aggressive | 750 mcg/kg | IV bolus, then 1.75 mg/kg/h infusion for the procedure |
This is a hospital-only IV drug. You won't be reconstituting this at home; cath lab pharmacists and nurses handle preparation under physician supervision. Reconstitution math for the record: each 250 mg vial gets 5 mL of Sterile Water for Injection (SWFI), giving a 50 mg/mL concentrate. That concentrate then gets diluted into 50 mL of D5W or 0.9% NaCl for a final working concentration of 5 mg/mL. For an 80 kg patient, the bolus is 60 mg (0.75 mg/kg x 80 kg), which works out to 12 mL from the 5 mg/mL solution. The procedural infusion runs at 140 mg/h (1.75 mg/kg/h x 80 kg), so 28 mL/h from the same bag. The non-obvious thing most clinicians miss early on: a subtherapeutic ACT at the 5-minute check almost always traces back to a weight calculation error. Recheck actual body weight before giving the supplemental 0.3 mg/kg bolus. Estimated weights in emergency STEMI settings cause real dosing errors.
Dosing based on ANGIOMAX (bivalirudin) FDA Prescribing Information (2019) — 10 published references.View all sources →
Cross-check your Bivalirudin (Angiomax) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.