Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 202611 Citations
Beginner, moderate, and aggressive dosing amounts with timing. Free, no signup.
Topical
Argireline has no standard bacteriostatic water volume on file, so there are no syringe units to calculate here. Dosing runs 2mg to 10mg per administration, 2x daily. A 5mg supply covers about 2 doses at the beginner tier.
If your product does arrive as a powder, use the universal reconstitution calculator and enter your own vial size and water volume.
Argireline is a topical hexapeptide that inhibits SNARE complex assembly to soften expression wrinkles. Clinical results range from 48.9% efficacy to no significant effect across controlled trials. At $10 per bottle, it's worth testing on your own skin before drawing conclusions.
View side effects and safety warnings →
| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 2mg | 2x Daily |
| Moderate | 5mg | 2x Daily |
| Aggressive | 10mg | 2x Daily |
Start with a 5% concentration for the first two weeks if your skin runs reactive. One study landed on nearly identical wrinkle reduction at 5% vs. 10% (16.26% vs. 17%), so you're not losing much during the tolerance phase. After that, step up to 10% twice daily. Argireline is a topical peptide, not an injectable. There's no vial to reconstitute, no bacteriostatic water, no syringe math. You're buying a ready-to-use serum or cream. The Ordinary's 10% solution at $10 for 30ml is the community benchmark; use it to calibrate your expectations before spending more on premium formulations. The thing most beginners miss: check the label carefully. Some products list "contains Argireline" when the peptide is a trace ingredient in a blend. You want 10% Acetyl Hexapeptide-8 as the active, listed early in the INCI order. Apply to clean, dry skin before moisturizer. Morning and evening. Give it 2 to 3 minutes to absorb before layering. Refrigerate opened bottles and use within six months.
Dosing based on Cosmeceutical industry standard concentrations — 15 published references.View all sources →
Cross-check your Argireline reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →