Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 202610 Citations
Apelin-1212 residuesRPRLSHKGPMPFEach bubble = one amino acid. Size = residue mass. Color = chemical class.Turns your vial size, BAC water, and dose into exact syringe units. Free, no signup.
Adjust vial, water, and dose — answer updates live
All three take the same units for the same dose. A smaller barrel just spreads it over more space.
on a U-100 syringe for a 50mcg dose
Add 2 mL BAC water to your 2 mg vial. Draw to 5.0 units on a U-100 syringe for a 50mcg dose. This vial will last 40 doses.
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Never miss a dose — 50mcg daily, draw 5.0 units on U-100 syringe.
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Apelin-12 produced the strongest blood pressure reduction of any apelin isoform in rat studies, dropping MAP by 26 mmHg at a single IV dose. Plasma half-life sits around five minutes. Zero human clinical trials exist for native apelin-12. Strictly a preclinical research compound.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 50mcg | Daily |
| Moderate | 150mcg | Daily |
| Aggressive | 300mcg | Daily |
Reconstitution math for a 2 mg vial: add 2 mL bacteriostatic water to get 1 mg/mL (1000 mcg/mL). At that concentration, the beginner dose of 50 mcg is 5 units on a 100-unit insulin syringe. Moderate (150 mcg) is 15 units. Aggressive (300 mcg) is 30 units. With a 5 mg vial and 2 mL bacteriostatic water, you get 2.5 mg/mL (2500 mcg/mL). Beginner dose becomes 2 units. Moderate is 6 units. Aggressive is 12 units. Reconstituted apelin-12 lasts about 7 days at 2 to 8 degrees Celsius. Don't prep more than a week's supply at a time. Lyophilized powder stores well at minus 20 degrees with desiccant. The five-minute half-life is the elephant in the room. Every impressive rat data point used IV bolus dosing. SC absorption kinetics for apelin-12 have never been measured in any species. If you see no BP response after two weeks at moderate dosing, inadequate SC bioavailability is the most likely explanation. You need a blood pressure cuff before you need a syringe. Baseline BP is not optional.
Dosing based on Very limited human data: dose based on preclinical research — 14 published references.View all sources →
Based on a 2mg vial, 2mL of bacteriostatic water, the beginner dose (50mcg), and a U-100 syringe. Change any input in the calculator and every line moves with it.
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Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
