Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20269 Citations
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All three take the same units for the same dose. A smaller barrel just spreads it over more space.
on a U-100 syringe for a 10mcg dose
Add 2 mL BAC water to your 1 mg vial. Draw to 2.0 units on a U-100 syringe for a 10mcg dose. This vial will last 100 doses.
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Never miss a dose — 10mcg 3x daily, draw 2.0 units on U-100 syringe.
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Amylin (IAPP) is the pancreatic hormone behind pramlintide and cagrilintide. Thirty-seven amino acids, co-secreted with insulin, toxic when it misfolds. Research-only peptide with well-characterized glucose and satiety signaling but no safe path to clinical use in its native form.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 10mcg | 3x Daily |
| Moderate | 25mcg | 3x Daily |
| Aggressive | 50mcg | 3x Daily |
This is a research reagent, not a therapeutic peptide. If you're looking for amylin replacement therapy, pramlintide (Symlin) is the FDA-approved option with three proline swaps that stop aggregation. Reconstitution math for a 1 mg vial: add 2 mL acidic buffer (pH 3 to 4). That gives you 500 mcg/mL. At 10 mcg per dose, each injection is 0.02 mL, which is 2 units on a U-100 insulin syringe. At 25 mcg, it is 5 units. At 50 mcg, it is 10 units. For a 5 mg vial with 2 mL, you get 2,500 mcg/mL; 50 mcg would be 0.02 mL (2 units). Use the 1 mg vial for research dosing accuracy. The thing most beginners miss: you cannot reconstitute native IAPP in standard bacteriostatic water at neutral pH. Aggregation begins within hours. You need acidic buffer (pH 3 to 4), or HFIP pre-treatment. Dissolve in hexafluoroisopropanol, lyophilize into aliquots, reconstitute fresh. Prepare only the volume you need right before use. Discard anything with haziness or particulates; that is aggregated IAPP, and it is both inactive and cytotoxic.
Dosing based on Research peptide; pramlintide (Symlin) is the clinical analog: dose not interchangeable — 13 published references.View all sources →
Based on a 1mg vial, 2mL of bacteriostatic water, the beginner dose (10mcg), and a U-100 syringe. Change any input in the calculator and every line moves with it.
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Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.