Not medical advice. Talk to your provider before using any peptide.
Full disclaimerPeptide Schedule Research TeamReviewed Apr 20266 Citations
Alpha-MSH (α-Melanocyte-Stimulating Hormone)13 residues (approx.)SYSMEHFRWGKPVEach bubble = one amino acid. Size = residue mass. Color = chemical class.Uses closest standard amino acids for non-standard residues.Alpha-MSH is the parent peptide behind the melanocortin anti-inflammatory pathway, backed by 6,500+ published studies. Two FDA-approved drugs target the same receptor family. Native alpha-MSH's 20-minute half-life limits practical use; most users choose KPV, its active C-terminal fragment, for anti-inflammatory applications instead.
100mcg · Daily
Summary: Add 2mL BAC water to your 1mg vial. Draw to 20.0 units on a U-100 syringe for a 100mcg dose. This vial will last 10 doses.
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| Level | Dose / Injection | Frequency |
|---|---|---|
| Beginner | 100mcg | Daily |
| Moderate | 250mcg | Daily |
| Aggressive | 500mcg | Daily |
Alpha-MSH is not a community peptide. It's a research reference compound, and the practical realities reflect that. Most people looking for melanocortin anti-inflammatory effects should consider KPV first; it's cheaper, more stable, and doesn't cause pigmentation. Reconstitution math for a 1 mg vial: add 2 mL bacteriostatic water. That gives you 500 mcg/mL, or 5 mcg per unit on a 100-unit insulin syringe. A 100 mcg beginner dose is 20 units. A 250 mcg moderate dose is 50 units. For a 5 mg vial with 2 mL BAC water: 2,500 mcg/mL, or 25 mcg per unit. A 250 mcg dose is 10 units. A 500 mcg dose is 20 units. The 5 mg vial is better value if you're running a full 8-week protocol. Alpha-MSH degrades faster than most peptides after reconstitution. Keep it at 2 to 8 degrees Celsius and use within 14 days. Don't freeze and thaw repeatedly. If the solution goes cloudy, throw it out. Source from established research chemical suppliers (Sigma-Aldrich, Tocris, MedChemExpress), not grey-market peptide vendors. Expect to pay $80 to $250 per milligram for genuine research-grade product.
Dosing based on Research peptide; approved melanocortin agonists differ in dose and formulation — 10 published references.View all sources →
Cross-check your Alpha-MSH (α-Melanocyte-Stimulating Hormone) reconstitution math with AI
Pricing updated 2026-04-09
Prices are estimates and vary by source, location, and prescription status.Full pricing breakdown →
Disclaimer: This curve is a simplified first-order exponential decay model. Actual pharmacokinetics vary based on injection site, individual metabolism, body composition, and other factors. Half-life values are approximate and based on available preclinical and clinical literature. Many research peptides lack formal human pharmacokinetic studies. This is for educational purposes only — not medical advice.
Alpha-MSH is the parent peptide behind the melanocortin anti-inflammatory pathway, backed by 6,500+ published studies. Two FDA-approved drugs target the same receptor family. Native alpha-MSH's 20-minute half-life limits practical use; most users choose KPV, its active C-terminal fragment, for anti-inflammatory applications instead.
